Can amino-functionalized carbon nanotubes carry functional nerve growth factor？-中国期刊网

摘要 Carbonnanotubescancarryproteinintocellstoinducebiologicaleffects.Amino-functionalizedcarbonnanotubesaresolubleandbiocompatible,havehighreactivityandlowtoxicity,andcanhelppromotenervecellgrowth.Inthisstudy,amino-functionalizedethylenediamine-treatedmulti-walledcarbonnanotubeswereusedtopreparecarbonnanotubes-nervegrowthfactorcomplexesbynon-covalentgrafting.Thephysicochemicalproperties,cytotoxicitytoPC12andchickembryodorsalrootganglion,andbiologicalactivityofthecarbonnanotubes-nervegrowthfactorcomplexeswereinvestigated.Theresultsshowedthataminofunctionalizationimprovedcarbonnanotubes-nervegrowthfactorcomplexdispersibility,reducedtheirtoxicitytoPC12cells,andpromotedPC12celldifferentiationandchickembryodorsalrootganglion.

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Can amino-functionalized carbon nanotubes carry functional nerve growth factor？

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Can amino-functionalized carbon nanotubes carry functional nerve growth factor？

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