摘要
Theliteratureshowsthatimprovementsincognitiveperformancemaybeobservedfollowinganacuteboutofexercise.However,evidenceinsupportofthebiologicalmechanismsofthiseffectisstilllimited.Findingsfrombothrodentandhumanstudiessuggestbrain-derivedneurotrophicfactor(BDNF)asapotentialmechanismoftheeffectofacuteexerciseonmemory.ThemolecularpropertiesofBDNFallowthisproteintobeassessedintheperiphery(pBDNF)(i.e.,bloodserum,bloodplasma),makingmeasurementsofacuteexercise-inducedchangesinBDNFconcentrationrelativelyaccessible.StudiesexploringtheacuteexerciseepBDNFecognitiveperformancerelationshiphavehadmixedfindings,butthismaybemorereflectiveofmethodologicaldifferencesbetweenstudiesthanitisastatementabouttheroleofBDNF.Forexample,significantassociationshavebeenobservedbetweenacuteexercise-inducedchangesinpBDNFconcentrationandcognitiveperformanceinstudiesassessingmemory,andnon-significantassociationshavebeenfoundinstudiesassessingnon-memorycognitivedomains.ThreesuggestionsaremadeforfutureresearchaimedatunderstandingtheroleofBDNFasabiologicalmechanismofthisrelationship:1)Assessmentsofcognitiveperformancemaybenefitfromafocusonvarioustypesofmemory(e.g.,relational,spatial,long-term);2)MorefinegrainedmeasurementsofpBDNFwillallowfortheassessmentofconcentrationsofspecificisoformsoftheBDNFprotein(i.e.,immature,mature);3)StatisticaltechniquesdesignedtotestthemediatingroleofpBDNFintheacuteexercise-cognitiveperformancerelationshipshouldbeutilizedinordertomakecausalinferences.
出版日期
2015年01月11日（中国期刊网平台首次上网日期，不代表论文的发表时间）
