摘要
【摘要】 目的：通过子宫肌瘤剔除与子宫全切术治疗子宫肌瘤患者的临床对比研究，探讨子宫全切术对患者卵巢功能的影响。方法： 2016年 1月 -2017年 1月在本院住院的 90例子宫肌瘤患者按就诊顺序分成子宫肌瘤剔除组和子宫全切组，监测患者术前、术后 6个月、 12个月雌二醇（ E2）、促卵泡激素（ FSH）、黄体生成素（ LH）水平，观察卵巢功能。结果：两组患者术前性激素（ E2、 FSH、 LH）比较差异无统计学意义（ t=0.17、 0.65、 1.04， P>0.05），而术后 6个月，两组性激素比较差异有统计学意义（ t=6.14、 4.15、 3.71， P<0.05）。术后 12个月，两组性激素比较差异有统计学意义（ t=5.12、 3.89、 4.65， P<0.05）。术后 6个月子宫肌瘤剔除组月经不规律（月经量少、稀发或周期延长）均明显少于子宫全切组，差异有统计学意义（字 2=1.43， P<0.05）。术后 12个月子宫肌瘤剔除组月经不规律明显少于子宫全切组，差异有统计学意义（字 2=5.29， P<0.05）。结论：行子宫肌瘤剔除术治疗子宫肌瘤，卵巢内分泌功能稳定，而子宫全切术直接影响卵巢功能。
【关键词】 子宫肌瘤； 子宫全切术； 子宫肌瘤剔除术； 卵巢功能
[abstract] Objective: To investigate the effect of total hysterectomy on ovarian function of patients with hysteromyoma by comparing hysteromyomectomy with total hysterectomy. Methods: From January 2016 to January 2017, 90 patients with hysteromyoma were divided into hysteromyomectomy group and hysterectomy group according to the order of visits. The levels of estradiol (E2), follicle stimulating hormone (FSH) and luteinizing hormone (LH) were monitored before, 6 months and 12 months after operation, and the ovarian function was observed. Results: There was no significant difference in sex hormones (E2, FSH, LH) between the two groups before operation (t = 0.17, 0.65, 1.04, P > 0.05), but there was significant difference in sex hormones between the two groups 6 months after operation (t = 6.14, 4.15, 3.71, P < 0.05). At 12 months after operation, there were significant differences in sex hormones between the two groups (t = 5.12, 3.89, 4.65, P < 0.05). The irregular menstruation (less menstrual volume, sparse or prolonged cycle) in the myomectomy group was significantly less than that in the total hysterectomy group at 6 months postoperatively (word 2 = 1.43, P < 0.05). The irregularity of menstruation in the myomectomy group was significantly less than that in the hysterectomy group at 12 months postoperatively (word 2 = 5.29, P < 0.05). Conclusion: Uterine myomectomy has stable ovarian endocrine function in the treatment of uterine leiomyoma, and total hysterectomy directly affects ovarian function.
出版日期
2019年12月17日（中国期刊网平台首次上网日期，不代表论文的发表时间）
