摘要
[摘要 ] 目的 探讨米非司酮对复发性子宫内膜异位症的疗效及卵巢功能的影响。 方法 将 108例复发性子宫内膜异位症患者随机分为观察组和对照组，观察组采用米非司酮片治疗，对照组采用达那唑胶囊治疗，观察两组的临床治疗效果。 结果 治疗后观察组患者性交痛、痛经改善率显著高于对照组， 差异有统计学意义（ P<0.05）；治疗后两组 LH、 FSH、 E2及 T与子宫内膜厚度比较，差异有统计学意义（ P<0.05）；观察组停药后恢复月经时间低于对照组，差异有统计学意义（ P<0.05）。观察组不良反应发生率显著低于对照组，差异有统计学意义（ P<0.05）。 结论 米非司酮治疗复发性子宫内膜异位症效果显著，改善卵巢功能，不良反应少，值得临床推广。
[关键词 ] 米非司酮；复发性子宫内膜异位症；卵巢功能；达那唑
[Abstract] Objective To investigate the effect of mifepristone on recurrent endometriosis and ovarian function. Methods 108 patients with recurrent endometriosis were randomly divided into the observation group and the control group. The observation group was treated with mifepristone tablet and the control group with danazol capsule. Results after treatment, the improvement rate of coital pain and dysmenorrhea in the observation group was significantly higher than that in the control group (P < 0.05); after treatment, the difference between LH, FSH, E2 and T and endometrial thickness in the two groups was statistically significant (P < 0.05); the recovery time of menstruation in the observation group was lower than that in the control group (P < 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion mifepristone is effective in the treatment of recurrent endometriosis. It can improve ovarian function and has few adverse reactions. It is worthy of clinical application.
出版日期
2020年08月11日（中国期刊网平台首次上网日期，不代表论文的发表时间）
