摘要
[摘要 ]目的：探讨常规治疗基础上给予泮托拉唑治疗非静脉曲张性上消化道出血的临床效果。方法：在医院 2015年 3月至 2019年 3月期间诊治的非静脉曲张性上消化道出血患者中选取 100例作为研究对象，并按治疗方案不同分组：将应用常规治疗者设为对照组（ n=50），将应用常规治疗联合泮托拉唑方案者设为研究组（ n=50），就 2组患者止血效果以及不良反应发生率差异进行统计学分析。结果：①研究组患者止血治疗有效率（ 98.0%）高于对照组（ 84.0%）（ x2=4.396， P=0.036） ;②研究组不良反应发生率与对照组相比无统计学差异（ x2=0， P=1.000）。结论：非静脉曲张性上消化道出血患者应用常规治疗联合泮托拉唑方案，可进一步优化止血效果，且无明显不良反应，兼顾了用药有效性、安全性。
[关键词 ]常规治疗 ;泮托拉唑 ;非静脉曲张性上消化道出血
[Abstract] Objective: To investigate the clinical effect of pantoprazole on non varicose upper gastrointestinal hemorrhage. Methods: from March 2015 to March 2019, 100 patients with non variceal upper gastrointestinal bleeding were selected as the study object and divided into different groups according to the treatment plan: the patients who applied the conventional treatment were set as the control group (n = 50), and the patients who applied the conventional treatment combined with pantoprazole were set as the study group (n = 50). The hemostatic effect and the incidence of adverse reactions of the two groups were studied The differences were statistically analyzed. Results: ① the effective rate of hemostasis in the study group (98.0%) was higher than that in the control group (84.0%) (x2 = 4.396, P = 0.036); ② the incidence of adverse reactions in the study group was not statistically different from that in the control group (x2 = 0, P = 1.000). Conclusion: the routine treatment combined with pantoprazole can further optimize the hemostasis effect in patients with non varicose upper gastrointestinal bleeding, and there is no obvious adverse reaction, and the effectiveness and safety of the drug are also considered.
出版日期
2020年08月18日（中国期刊网平台首次上网日期，不代表论文的发表时间）
