学科分类
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2 个结果
  • 简介:AmodelofcrosslinkerunbindingisimplementedinahighlycoarsegrainedgranularmodelofF-actincytoskeleton.WeemploythisspecificgranularmodeltostudythemechanismsofthecompressiveresponsesofF-actinnetworks.ItisfoundthatthecompressiveresponseofF-actincytoskeletonhasdependencyonthestrainrate.TheevolutionofdeformationenergyinthenetworkindicatesthatcrosslinkerunbindingeventscaninducetheremodellingofF-actincytoskeletoninresponsetoexternalloadings.TheinternalstressinF-actincytoskeletoncanefficientlydissipatewiththehelpofcrosslinkerunbinding,whichcouldleadtothespontaneousrelaxationoflivingcells.

  • 标签: F-肌动蛋白 物理机制 交联剂 绑定 网络 肌动蛋白细胞骨架