简介：BackgroundThrombocytopeniaisacommoncomplicationofIABP.Untilnow,thereisnounifiedconclusionsabouttheincidence,characteristics,riskfactorsandtheprognosisofIABPrelatedthrombocytopenia.MethodsInthisstudy,thedataofpatientswithACSundergoingPCIandIABPwereretrospectivelyanalyzed.Allenrolledpatientsweredividedintothrombocytopeniagroupandnon-thrombocytopeniagroupaccordingtotheoccurrenceofthrombocytopeniaafterinsertionofIABP.Thebaselinedataofthetwogroupswerecompared,andthepossibleriskfactorsofthrombocytopeniaandtheirimpactonprognosiswereanalyzedbychi-squaretestandlogisticregressionanalysis.ResultsSixty-twopatientswereenrolledinthisstudy.TherateofIABPassociatedthrombocytopeniawas25.8%(16/62)ofallpatients.OlderagewasanindependentriskfactorofIABPassociatedthrombocytopenia(OR:3.625;95%confidenceinterval:1.016-12.935;P=0.047).TheincidenceofTIMIbleedingeventswashigherinthrombocytopeniagroup[75.0%(12/16)vs.43.5%(20/46),P=0.042].Therateofin-hospitaldeathwassimilarbetweenthetwogroups[18.8%(3/16)vs.17.4%(8/46),P=1.0].ConclusionIABPassociatedthrombocytopeniaoccursin25.8%ofpatientswithACSundergoingPCIandcorrelateswithincreasedTIMIbleedingevents.OlderagemaypredictIABPassociatedthrombocytopenia.

简介：backgroundToinvestigatetheeffectofintra-aorticballoonpumping(IABP)onno-reflowphenomenoninprimarypercutaneouscoronaryintervention(PCI)forST-ElevationMyocardialInfarction(STEMI).MethodsClinicaldataof22acutemyocardialinfarctionpatientsafterPCIwithangiographicno-reflowphenomenonwereretrospectivelyanalyzedbetweenJanuary2006andDecember2009.12patientsunderwentIABP,other10patientsascontrolgroup.Weobserveddifferenceofcardiacstructure,brainnatriureticpeptide(BNP)andventricularsystolicfunctionbetweentwogroup,aswellascardiacinjurymarkers(MYO,CK-MB,cTnI)inbothgroupsonthedaysof1,2,3,5,7,10afterthedifferentinterventions.Inaddition,cardiacstructureandventricularsystolicfunctionincludingleftatriummedialdiameter(LAMD),leftventricularmedialdiameter(LVMD),leftventricularejectionfraction(LVEF)wasevaluatedafter10days,3months,6months.Finally,statisticswasusedtoanalysisthedata.ResultsTheseveralvasoactivesubstancesaswellascardiacinjurymarkersandLAMD,LVMD,LVEFof10days,3months,6monthsofIABPgroupweresignificantdifferencewithcontrolgroup(P<0.05).BNPtargetsofIABPgroupcomparedwiththecontrolgroupnosignificantdifference(P>0.05).ConclusionsIABPhaseffectsonprognosisinSTEMIpatientswhoperformedPCIwithangiographicno-reflowphenomenon,whichisconducivetorecoveryofheartfunction.

简介：BackgroundIntra-aorticballoonpump(IABP)hasbeenwidelyusedatpresent.Wecanuseitatdifferentstagesofperioperativeperiodinoff-pumpcoronaryarterybypassgrafting(CABG).However,whentouseditwasseldomconfirmed.MethodsFromJanuary2008toJune2012,the89coronaryheartdisease(CHD)patientsacceptedimplantationofIABPatdifferentstagesofoff-pumpCABG,preoperativeandpostoperativeventricularsystolicfunction,leftventricularremodelingsituationandthechangesofmyocardialenzymeswereevaluated.ResultsAllthepatientshadleftheartinsufficiencyandmultivesseldisease.TheirpostoperativeleftventricularsystolicfunctionandventricularremodelingweresignificantlyimprovedwhilemyocardialenzymesdecreasedwithpreoperativeinterventionalimplantationofIABP.Theperioperativemortalitywas7.86%(7/89).NopatientshadcomplicationofIABP.ConclusionEarlierIABPimplantationatpreoperationisusefultoimproveheartfunction,improvethetolerabilityofsurgery,reducetheincidenceofpostoperativelowcardiacoutputsyndrome(LCOS)anddecreasethemortality.