简介:StudyoncorrelativityamongcapacitydimensionD0,infor-mationdimensionD1,algorithmiccomplexityC(n)andbValueWEI-BINHAN(韩渭宾),GUI-X...
简介:凌源-宁城盆地是松辽盆地外围南部众多具良好油气勘探前景的小盆地之一,为研究其中的油气资源情况,在牛营子地区部署和实施了油气地质调查井——牛D1井。该钻井揭示侏罗系海房沟组可能为研究区重要的烃源岩发育层系之一。系统采集了海房沟组岩心,对其进行了岩石热解、镜质体反射率、气相色谱-质谱等分析及有机地球化学研究。结果表明,海房沟组浅部多为好-很好烃源岩,而深部多为差烃源岩和非烃源岩,有机质类型均主要为Ⅱ_2和Ⅲ型;浅部烃源岩的三环萜烷、升藿烷和甾烷系列丰度较高,规则甾烷呈不对称"V字型";而深部烃源岩的三环萜烷、升藿烷和甾烷系列丰度较低,规则甾烷多呈"反L型"。综合认为海房沟组浅部具有相对较强的生烃潜力,但牛D1井海房沟组烃源岩的成熟度较低,建议今后加强对海房沟组烃源岩展布和成熟度平面分布特征的研究。
简介:Cytarabine(1-β-D-arabinofuranosylcytosine,Ara-C),isolatedfromaCaribbeanspongespeciesTethyacrypta,isthefirstantitumordrugfromamarineresource.In1980,theUSFoodandDrugAdministrationapprovedthisdrugforthetreatmentofdifferenttypesofleukemia.Thisdrughasashortplasmahalf-life,lowstability,limitedbioavailability,andseveresideeffects.Toimprovestabilityandbioavailability,wesynthesizedninenovelderivativesbyblockingthecytarabinemetabolicsitesandimprovinglipophilicity.ThecLogPvaluesofthenewlysynthesizedcompoundswerecalculated.Allthesynthesizedcompoundsweremorelipophilicthancytarabine,resultinginmembranepermeabilityandbioavailabilityimprovement.TheantitumoractivitiesagainstleukemiacelllineHL-60wereevaluatedbyusingtheMTTassay.ThebioassayresultsrevealedthattheIC50valuesofcompounds5,8and9were0.080,0.090and0.057μmolL-1,respectively,whichwassimilarwiththatofcytarabine(0.056μmolL-1).Incomparison,compound4withaphosphategroupatO5’wasinactive.Becausephosphoesterbondsareeasilyhydrolyzedbyalkalinephosphataseandarecommonlyusedinproducingprodrugstrategies,compound4mightalsobemetabolizedinvivoandgeneratecompound3orevencytarabinethroughamulti-stepreaction.Thus,compound4mightbeapromisingcompoundtobedevelopedasaprodrug.
简介:通常一个维(1-D)实验咸度侵入模型被限制到自然冲积河口。然而,这研究试图调查它的能力在马来西亚为Terengganu河的一个掩盖的冲积河口建模。在河的嘴的构造防波提从公海的直接影响掩盖河口。沿着河口的咸度密度被收集在期间湿并且为在构造防波提前后的情形的旱季。而且,淡水分泌物,潮汐的举起和深测术数据也作为模型输入被测量。一好合适在模仿并且观察的变量之间被表明,也就是为两种情形的咸度分发和侵入长度。因此,结果显示出那1-D实验咸度模型能在Terengganu河口为掩盖的河口状况被利用,但是与一个起始的点的一颗适当决心。而且,在学习区域的咸度侵入大部分依赖于淡水分泌物而非潮汐的举起变化,这被观察。在学习区域的咸度侵入长度的规模与the-1/2力量的河分泌物成正比。实验咸度模型和分泌物驱动的1-D的二根线基于适合很好到对方的方程,这被显得,与150的平均预言的最小的淡水分泌物,m3/s将被要求在水吸入车站附近在高水位线呆滞(HWS)期间维持可接受的咸度层次,它从河嘴在10.63km被定位。
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简介:Athree-dimensionalrigidbodyontheshapeofaparallelepipedismodelledinordertorockonasideoravertexofthebase,inordertoevaluatetheseismicresponseofrigidblockslyingonahorizontalsupport.Thecenterofmassofthebodyisconsideredaseccentricwithrespecttoitsgeometriccenter.Asseismicinput,threeItalianrecordedaccelerograms,withdifferentspectralcontent,areused.Thestudyismainlyconductedtohighlightthedifferencesbetweentheseismicresponseof2Dand3Dmodelsofrigidblocks,withtheaimtounderstandif,insomecases,theuseofthe3Dmodelofrigidblockisrequiredtoobtainsaferresults.Infact,theoutcomesshowthatinsomerangesofthegeometricalandmechanicalparametersthatcharacterizetheexcitationandthebody,atwo-dimensionalmodel,whichisnotabletoconsiderthe3Drockingonavertex,canprovideunsaferesults.Inparticular,itisfoundthattheoverturningprocessofthethree-dimensionalblockcanoccurunderexcitationswhicharelowerthanthosewhichoverturnacorrespondingtwo-dimensionalblock.
简介:Withtherapiddevelopmentofglobalinformationhighway,multimediacommunicationtechnologyplaysamoreandmoreimportantroleinnationaleconomicandsocialdevelopment.However,themultimediacommunicationsystemisacomplicatedrealtimedistributedsystemanditssoftwareisdifficulttodevelop.Inordertoimprovetherapiddevelopmentandapplicationofthemultimediacommunicationtechnology,thereisanurgentneedtocarryoutthebasicresearchworkofsoftwaredevelopmentplatforminthisfield.
简介:Title:DiscontinuousDeformationAnalysisandRecentCrustalMovementAuthor:WANGZeminSupervisor:LIUJingnanThestudyfocusesonthewait_to_be_resolvedimportantdifficultproblem—howtoanalyzeandprocessthenumerousdataofcrustalmovementgainedbyrecentmeasuringmethodsoastodiscovertheinnermechanisms,thispaper,adopt