简介：编写说明外文音乐工具书比较中文音乐工具书来说,无论从数量还是质量上讲,都远远超过了中文音乐工具书。其原因在于国外的音乐学家们。音乐文献学家们都非常重视音乐参考工具书和检索工具的编撰。尤其是在参考书目和索引的编制方面,许多大学者为方便他人的研究与学习,不惜付出毕生心血去做我们许多学者不屑去做的二次文献的编制。笔者从事音乐图书馆工作十余年来,目睹许多研究人员和学生整日埋头书海、沙里淘金,虽为他们的钻研精神

简介：随着我国经济建设、经济体制改革的进一步发展和深入,人们终于认识到图书馆迎接市场经济的挑战已刻不容缓地摆在了我们面前。尤其是在党的十四大提出建立社会主义市场经济体制的新形势下,图书馆如何面向社会,面向市场经济,已成为研究图书馆

简介：Changesinneurocognitivefunctioningandqualityoflifeinadultpatientswithbraintumorstreatedwithradiotherapy.

简介：PURPOSE：Vorinostat,ahistonedeacetylaseinhibitor,representsarationaltherapeutictargetinglioblastomamultiforme（GBM）.PATIENTSANDMETHODS：PatientswithrecurrentGBMwhohadreceivedoneorfewerchemotherapyregimensforprogressivediseasewereeligible.

简介：Markedresponseofgliomatosiscerebritotemozolomideandwholebrainradiotherapy.

简介：PURPOSE：ResistancetotemozolomidechemotherapyispartlymediatedbyO^6-methylguanine-DNAmethlytransferase（MGMT）.ProtractedtreatmentwithtemozolomidepotentiallyovercomesMGMTresistanceandimprovesoutcome.WeconductedaphaseIIstudyofprotracteddailytemozolomideinadultswithlow-gradegliomas.EXPERIMENTALDESIGN：PatientswithnewlydiagnosedoligodendrogliomaoroligoastrocytomawithaMIB-1indexof〉5%orrecurrentlow-gradegliomasreceivedtemozolomide（75mg/m^2/dayin11-weekcyclesof7weekson/4weeksoff）.Treatmentcontinuedforatotalofsixcyclesoruntiltumorprogressionorunacceptabletoxicity.Primaryendpointwasbestoverallresponserate;secondaryendpointswereprogression-freesurvival,overallsurvival,andtoxicity.

简介：BACKGROUND：In2004,arandomisedphaseⅢtrialbytheEuropeanOrganisationforResearchandTreatmentofCancer（EORTC）andNationalCancerInstituteofCanadaClinicalTrialsGroup（NCIC）reportedimprovedmedianand2-yearsurvivalforpatientswithglioblastomatreatedwithconcomitantandadjuvanttemozolomideandradiotherapy.We＇reportthefinalresultswithamedianfollow-upofmorethan5years.METHODS：Adultpatientswithnewlydiagnosedglioblastomawererandomlyassignedtoreceiveeitherstandardradiotherapyoridenticalradiotherapywithconcomitanttemozolomidefollowedbyuptosixcyclesofadjuvanttemozolomide.

简介：Monochromaticminibeamsradiotherapy：fromhealthytissue-sparingeffectstudiestowardfirstexperimentalgliomabearingratstherapy.

简介：PURPOSE：Toevaluatethetoxicityandresponserateofbortezomibwithconcurrentradiotherapyandtemozolomideinthetreatmentofpatientswithcentralnervoussystemmalignancies.PATIENTSANDMETHODS：Thisopen-label,dose-escalation,PhaseⅠclinicalstudyevaluatedthesafetyofthreedoselevelsofintravenouslyadministeredbortezomib（0.7,1.0,and1.3mg/m（2）/dose）onDays1,4,8,and11ofa21-daycycle,inadditiontoconcurrentradiotherapyandtemozolomideatadailydoseof75mg/m（2）startingonDay1.Theprimaryendpointwasdose-limitingtoxicity,definedasanyGrade4-5toxicityorGrade3toxicitydirectlyat-tr/butabletoprotocoltreatment,requiringhospitalizationand/orradiotherapyinterruption.

简介：研发前言Rockwell科学公司开发高温SiC电机传动系统Rockwell科学公司与美国空军研究实验室将共同开发高效、高温和小型的电机传动系统,应用于飞机和太空船。该项目主要开发基于SiC(碳化硅半导体)开关的磁阻电机传动,检验在200℃工作的容错电气传动装置。开发这种能在几乎无冷却的恶劣环境下工作的电机传动系统,关键是研发高温SiC开关,封装,控制电子学和电机。这些装置将显著降低电力电子的尺寸和重量。

简介：PURPOSE：ThisphaseⅡtrialwasdesignedtodefinetheroleofO^6-benzylguanine（O^6-BG）inrestoringtemozolomidesensitivityinpatientswithrecurrentorprogressive,temozolomidc-resistantmalignantgliomaandtoevaluatethesafetyofadministeringO^6-BGincombinationwithtemozolomide.PATIENTSANDMETHODS：Patientswereaccruedintotwoindependentstrataonthebasisofhistology：glioblastomamultifonne（GBM）andaanaplasticglioma.BothtemozolomideandO6-BGwereadministeredonday1ofa28-daytreatmentcycle.Patientswereadministereda1-hourO^6-BGinfusionatadoseof120mg/m^2followedimmediatelybya48-hourinfusionatadoseof30mg/m^2/d.

简介：PURPOSE：Toevaluatesingle-agentactivityofbevacizumabinpatientswithrecurrentglioblastoma.PATIENTSANDMETH-ODS：Patientswithrecurrentglioblastomaweretreatedwithbevacizumab10mg/kgevery2weeks.Aftertumorprogression,patientswereimmediatelytreatedwithbevacizumabincombinationwithirinotecan340mg/m^2or125mg/m^2every2weeks,dependingonuseofenzyme-inducingantiepilepticdrugs.Completepatientevaluationswererepeatedevery4weeks.RESULTS：Forty-eightheavilypretreatedpatientswereaccruedtothisstudy.Thromboembolicevents（12.5%）,hypertension（12.5%）,hypophosphatemia（6%）,andthrombocytopenia（6%）werethemostcommondrug-associatedadverseevents.Sixpatients（12.5%）wereremovedfromstudyfordrug-associatedtoxicity（fivethromboembolicevents,onebowelperforation）.

简介：

简介：PURPOSE：Fotemustineisanitrosoureacompoundusedforthetreatmentofmalignantgliomas,especiallyinFrance.Recently,anEORTC-NCICstudyhasshownthataconcomitantcombinationofradiotherapyplustemozolomide（anoralcytotoxicdrug）improvedsurvivalinglioblastomapatients.Wesetouttotestaconcurrentcombinationofradiotherapyandfotemustinefornewlymalignantgliomas.

简介：BACKGROUND：SupratentorialPNET（sPNET）arerareCNStumorsofembryonaloriginarisinginchildrenandadults.Thetreat-mentofsPNETforallagegroupsatourcancercenterhasbeenbasedonthemanagementofmedulloblastoma（MB）,involvingneurosurgicaldebulkingfollowedbyeranio-spinalirradiation（CS1）andsystemicchemotherapy.METHODS：MedicalrecordswerereviewedtogatherdemographicandclinicaldataaboutallembryonalCNStumorsinchildrenandadultsfrom2001to2007.Tumorpathology,clinicalmanagementandsurvivaldatawerealsoassessed,particularlyasregardsthosepatientswhoreceivedthePackerchemotherapyregimenforeithersPNETorMB.

简介：汽车零部件再制造业中各单位合作管理的探讨汽车行业是历史最悠久的再制造业之一。其中再制造部件包括刹车钳、发动机、伺服油泵以及交流发电机。而对于实现再制造部件的稳定供货源,是汽车部件再制造业面临的巨大挑战。供货源是可以与核心供货商签订协议来确定,比如：原始再制造商们也可以广泛的寻找

简介：Humanglioblastomas(GBM)arethoughttobeinitiatedbygliomastem-likecells(GSLCs).GSLCsalsoparticipateintumorneovascularizationbytransdifferentiatingintovascularendothelialcells.Here,wereportacriticalroleofGSLCsintheformationofvasculogenicmimicry(VM),whichdefineschannelslinedbytumorcellstosupplynutrientstoearlygrowingtumorsandtumor

简介：Glioblastomaisoneofthemostangiogenichumantumorsandcharacterizedbymicrovascularproliferations.Abetterunderstandingofglioblastomavasculatureisneededtooptimizeanti-angiogenictherapythathasshownapromisingbutincompleteefficacy.Thepresentstudyexamined48glioblastomasbyCD34endothelialmarkerperiodicacid-Schiff(PAS)dualstainingandfoundnon-endothelialcell-linedblood

简介：RoleofEarlyPostradiationMagneticResonanceImagingScansinChildrenwithDiffuseIntrinsicPontineGlioma.

简介：Prophylacticantiepilepticdrugtherapyinpatientsundergoingsupratentorialmeningiomaresection：asystematicanalysisofefficacy.JNeurosurg.2011Jun3.[Epubaheadofprint]KomotarRJ,RaperDM,StarkeRM,IorgulescuJB,GutinPH.