简介：【摘要】目的：分析亲水性软性角膜接触镜用于治疗大泡性角膜病变和丝状角膜炎的临床效果。方法：实验数据样本选取我院于 2018年 1月至 2019年 1月期间收治的 120例大泡性角膜病变和丝状角膜炎患者 ,并按照随机的原则等分成两组进行对比实验（实验组和对照组），实验组和对照组患者均为 60例。对照组选用传统的药物治疗方式，实验组则在对照组的药物治疗基础上佩戴 亲水性软性角膜接触镜进行治疗。在治疗1周后，对临床症状的缓解和角膜上皮创面的愈合状况进行两组间比较。结果：临床症状完全缓解比率方面实验组显著优于对照组，存在差异，具有统计意义学（ P＜ 0.05）；对比治疗 1周后的角膜上皮愈合情况，丝状角膜炎实验组状况好于对照组，存在差异，具有统计意义学（ P＜ 0.05）。结论：选用亲水性软性角膜接触镜对大泡性角膜病变和丝状角膜炎进行治疗，能够及早缓解临床症状，减轻患者的苦楚，还能有效促进丝状角膜炎患者角膜上皮的恢复，值得在临床上推广运用。 Objective: to analyze the clinical effect of hydrophilic soft contact lens in the treatment of bullous keratopathy and filamentous keratitis. Methods: 120 patients with bullous keratopathy and filamentous keratitis treated in our hospital from January 2018 to January 2019 were selected and randomly divided into two groups (experimental group and control group). There were 60 patients in the experimental group and the control group. The control group was treated with traditional drug therapy, while the experimental group was treated with hydrophilic soft corneal contact lens on the basis of drug treatment in the control group. After a week of treatment, the clinical symptoms remission and the healing of corneal epithelial wound were compared between the two groups. Results: the complete remission rate of clinical symptoms in the experimental group was significantly better than that in the control group (P < 0.05), and the corneal epithelial healing in the experimental group with filamentous keratitis was better than that in the control group (P < 0.05). Conclusion: the treatment of bullous keratopathy and filamentous keratitis with hydrophilic soft contact lens can relieve the clinical symptoms and relieve the suffering of the patients as soon as possible, and can also effectively promote the recovery of corneal epithelial cells in patients with filamentous keratitis. It should be popularized and applied in clinic. [key words] hydrophilic soft corneal contact lens; bullous keratopathy; filamentous keratitis; clinical study 【关键词】亲水性软性角膜接触镜；大泡性角膜病变；丝状角膜炎；临床研究