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简介：瞄准：学习颜色的协会有侵略的癌，本地复发，synchronicity和损害的元慢性的表面的锯齿状腺瘤(SA)。方法：从在一个八年的时期(1987-1995)上的1,096个病人的4,536息肉的一个总数回顾地被检验。显示出至少50%serrated建筑学的腺瘤被三称为SA考察病理学家。结果：(2%)91所有息肉被称为SA，它在46个病人被发现。侵略的癌从46在3被看见(6.4%)病人，一个人是家庭腺瘤息肉病(FAP)的一个盒子。男优势被注意，发育异常的温和的度的特征在多数被看见(n=75，83%)锯齿状腺瘤。后续变化了有5.75年的一吝啬的时间的1-12年。SA的复发在3被看见(6.4%)盒子，在16的同步SA(34.8%)在9的盒子和异时SA(19.6%)盒子。结论：侵略的癌在锯齿状腺瘤产生是稀罕的，为2的财务(4.3%)在这个系列的casesstudied。

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简介：BACKGROUND:Ithasbeenreportedthatperoxisomeproliferator-activatedreceptorγ(PPARγ)ishighlyexpressedinlungcancer,coloncancer,andgastriccancer,aswellasothertumors.OBJECTIVE:TostudyexpressionofPPARγinpituitaryadenomasandanalyzetheroleofPPARγinhormonaltypingofpituitaryadenomas.DESIGN,TIMEANDSETTING:Semi-quantitativeimmunohistochemistryofpathologicalspecimens.TheexperimentwasconductedattheDepartmentofNeurosurgery,WuxiSecondHospitalAffiliatedtoNanjingMedicalUniversitybetweenJanuary2002andMay2005.MATERIALS:Surgicalresectionsamplesofpituitaryadenomasfrom38cases(18maleand20female)wereanalyzed.Eightcasesweredeterminedtobeinvasivepituitaryadenomasand30caseswerenon-invasivepituitaryadenomas.Hormonalclassificationofthetypesofpituitaryadenomasrevealedsomatotrophicadenomasinsixcases,corticotrophicadenomainfivecases,prolactinomasin13cases,multi-hormonesecretingadenomasinsixcases,andeightcasesofadenomawithoutalteredendocrinefunction.Fiveautopsyspecimenswerecollectedduringthesameperiodfrompatientsofmatchingagethatdiedfromunrelateddiseasesandwereincludedasnormalanteriorpituitarycontrols.METHODS:Cellcountsforpositiveimmunohistochemicalsignalswererecordedfromhistopathologicalsections.Thepercentageofpositivecellswasreportedasasemi-quantitativeanalysis.MAINOUTCOMEMEASURES:TherateofPPARγpositivecellsindifferenttypesofadenomawasbasedonhormonallevelsandinvasivenessofpituitarytumorcells.RESULTS:AlltumorbiopsiesweredeterminedtoexpressPPARγTherateofPPARγ-positivecellsrangedbetween8%-65%inthepituitaryadenomas.Accordingtohormonaltype,PPARγexpressiondidnotvarybetweenthegroups.Inaddition,therewasnosignificantdifferenceinPPARγexpressionbetweenthenon-invasiveandinvasivepituitaryadenomas.CONCLUSIONS:HumanpituitaryadenomasexpressPPARγ,andthisexpressionisunrelatedto

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