简介:AbstractBackground:The prevalence of skin diseases and diabetes mellitus (DM) are prominent around the world. The current scope of knowledge regarding the prevalence of skin diseases and comorbidities with type 2 DM (T2DM) is limited, leading to limited recognition of the correlations between skin diseases and T2DM.Methods:We collected 383 subjects from the Da Qing Diabetes Study during the period from July 9th to September 1st, 2016. The subjects were categorized into three groups: Normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and T2DM. The prevalence and clinical characteristics of skin diseases were recorded and investigated.Results:In this cross-sectional study, 383 individuals with ages ranging from 53 to 89-year-old were recruited. The overall prevalence of skin diseases was 93.5%, and 75.7% of individuals had two or more kinds of skin diseases. Additionally, there were 47 kinds of comorbid skin diseases in patients with T2DM, of which eight kinds of skin diseases had a prevalence >10%. The prevalence of skin diseases in NGT, IGT, and T2DM groups were 93.3%, 91.5%, and 96.6%, respectively; stratified analysis by categories showed a statistically significant difference in "disturbances of pigmentation" and "neurological and psychogenic dermatoses" . The duration of T2DM also significantly associated with the prevalence of "disturbances of pigmentation" and "neurological and psychogenic dermatoses" . Subsequently, the prevalence of "disturbances of pigmentation" was higher in males than females in NGT (P < 0.01) and T2DM (P < 0.01) groups. In addition, the difference in the prevalence of "disturbances of pigmentation" was also significant in NGT and T2DM groups (P < 0.01).Conclusions:There was a high prevalence of skin diseases in the Da Qing Diabetes Study. To address the skin diseases in the Da Qing Diabetes Study, increased awareness and intervention measures should be implemented.
简介:摘要:DA42NG飞机的螺旋桨由发动机电子控制系统EECS控制。螺旋桨系统的自检被设计用于模拟配备传统机械式螺旋桨操纵的手动试车测试。其目的是为了验证螺旋桨调速功能是否正常。并且可以记录下各种非正常状况下的具体过程,供排除故障时参考。本文通过对DA42NG飞机发动机ECU和螺旋桨自检逻辑的剖析,对实际工作中遇到的典型故障进行分析,使维修人员能够有针对地排除故障。
简介:摘要目的评价DA-JC4预处理对睡眠剥夺老龄大鼠认知功能的影响。方法清洁级健康雄性SD大鼠36只,18~22月龄,体重500~600 g,采用随机数字表法分为3组(每组12只):对照组(C组)、睡眠剥夺组(S组)和DA-JC4组(D组)。S组和D组采用改良多平台水环境法建立老龄大鼠睡眠剥夺模型。D组每天10:00腹腔注射DA-JC4 25 nmol/kg(溶于1 ml生理盐水中),连续注射6 d,C组和S组于相同时间腹腔注射等量生理盐水。大鼠于睡眠剥夺结束后行Morris水迷宫实验,连续4 d,记录各组小鼠穿越平台次数及目标象限停留时间。于第5天水迷宫实验结束后处死大鼠取海马组织,采用ELISA法检测海马组织IL-1β、TNF-α含量,采用Western blot法检测海马细胞核NF-κB p65表达。结果与C组比较,S组和D组Morris水迷宫实验穿越平台次数减少,目标象限停留时间缩短,海马组织IL-1β、TNF-α含量增加,海马细胞核NF-κB p65表达上调(P<0.05);与S组比较,D组Morris水迷宫实验穿越平台次数增多,目标象限停留时间延长,海马组织IL-1β、TNF-α含量降低,NF-κB p65表达下调(P<0.05)。结论DA-JC4预处理可改善睡眠剥夺老龄大鼠的认知功能,其机制可能与抑制海马组织炎性反应有关。
简介:摘要:凝结水溶氧是发电厂化学监督的重要指标之一,近两年#6、#8机组凝结水含氧量一直都维持在较高水平,而随着凝结水溶氧过大,通过金属部件时会产生电化学腐蚀,对整个汽水循环系统造成伤害,给机组的安全性带来威胁。该文针对我单位M701DA燃机供热机组随着供热需求量的不断增大,机组补水量逐渐上升,运行中经常出现的凝结水溶解氧超标问题,从整个汽水系统着手,包括补水系统、凝汽器系统及机组其他相关组成部分,对导致凝结水溶氧超标的原因及其可能造成的危害、对应的治理措施进行汇总,以期为发电厂凝结水溶解氧治理提供借鉴意义。