简介:OrganicmodifierswereeffectivebothtoextendthemigrationtimewindowandtoimprovetheseparationofveryhydrophobiccompoundsinMEKC.Aniterationmethodwasusedtodeterminethemigrationtimeofmicelles.Thequantitativerelationshipbetweenthecapacityfactork’andtheconcentrationoforganicmodifierswasderived,whichwasinvestigatedexperimentally.Thelinearsolvationenergyrelationships(LSER)methodologywasappliedtoMEKC,andgoodlinearrelationshipsbetweenInk’andsolvatochromicparametersof15soluteswereobtainedinthepresenceoforganicmodifierindifferentconcentrations,whichindicatedanewaccessinMEKCtopredictk’fromthestructuralparametersofsolutes.TheeffectofcolumntemperatureTonk’wasalsoinvestigated.