简介：Ｍｅｄｏｇ　ＮｏＬｏｎｇｅｒ　Ａｎ　＇Ｉｓｏｌａｔｅｄ　Ｉｓｌａｎｄ＇ＭｅｄｏｇＮｏＬｏｎｇｅｒＡｎ＇ＩｓｏｌａｔｅｄＩｓｌａｎｄ＇￥ｂｙＮａｍｇｙａｉａｎｄＮｏｒｂｕｃｅｒｅｍｏｎｉｅｓａｒｅｈｉｌｄｉｎｂｏｔｈＺｈａｍｏｇａｎｄＭｅｄｏｇｔｏｉｎ...

简介：-Inthispaper,mathematicalmodelsanddynamicanalysesforbothSDOFandMDOFstructuresisolatedwithdampersareestablishedandperformed,andacomprehensivecomputationmethodisprovided.TheshockabsorbingeffectisillustratedthroughanexampleofatwoDOFdamper-isolatedsystemexcitedbysinusoidalwavesandactualgroundaccelerationinputrecordedinearthquakes.Itisshownthatmostoftheresponsesofthestructurewithdampersreducegreatlyneartheresonantzone,butaccelerationisenlargedinthelowerorhigherfrequencyzone;amongvariousparameters,theinfluenceoffrictionalcoefficientnisthemostsignificant,thatofdampingratioofthedampers,isthesecond,andthatofstiffnesscoefficientofthedampersk,istheslightest.

简介：Weisolatedandpurifiedmitochondriafrommouseliversandspinachleaves.WhenaddedintoeggextractsofXenopuslaevis,theycausednucleiofmouselivertoundergoapoptoticchanges.Chromatincondensation,marginationandDNAladderwereobserved.Afterincubatingisolatedmitochondriainsomehypotonicsolutions,andcentrifugingthesemixturesatmghspeed,wegotmitochondrialsupernatants.Itwasfoundthatintheabsenceofcytosolicfactor,thesupernatantalonewasabletoinduceapoptoticchangesinnuclei.Theeffectivecomponentswerepartlyofprotein.DNAfragmentationwaspartlyinhibitedbycaspaseinhibitorsAC-DEVD-CHOandAC-YVAD-CHO.Meanwhile,caspaseinhibitorsfullyblockedchromatincondensation.Primarycharacterizationofthenuclearendonuclease(s)inducedbymitochondrialsupernatantswasalsoconducted.ItwasfoundthatthisendonucleaseisdifferentfromendonucleaseG,cytochromec-inducednuclease,orCa^2+-activatedendonuclease.

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简介：ThepresentstudywasdesignedtoinvestigatethechemicalconstituentsofthewholeherbofDichrocephalabenthamii.Anewmegastigmaneglucoside(compound1),togetherwithitsfourknownanalogues(compounds2-5),wasobtained.Theirstructureswereelucidatedonthebasisofspectroscopicanalyses(UV,IR,MS,and1Dand2DNMR).Theabsoluteconfigurationofcompound1wasassignedonthebasisofCDmethodandchemicalevidence.Inaddition,theircytotoxicityagainsthumanhepatomacells(HepG-2)wasevaluatedbytheMTTmethod.Compound5showedweakactivityagainstHepG-2,whiletheothercompoundsdidnotshowremarkableinhibitoryeffects.

简介：Twonewlimonoids,12-ethoxynimbolininsGandH(compounds1and2),andoneknowncompound,toosendanin(Chuanliansu)(compound3),wereisolatedfromthebarkofMeliatoosendan.TheirstructureswereelucidatedbyspectroscopicanalysisandX-raytechniques.Theabsoluteconfigurationoftoosendanin(3)wasestablishedbysingle-crystalX-raydiffraction.Compounds1-3wereevaluatedfortheircytotoxicityagainstfivetumorcelllines.

简介：与称为超点阵的各种各样的配置覆盖同量的光格子能导致异国情调的格子拓扑学并且，接着新奇物理的发现。在这学习，由重叠格子的最大值，新孤立的结构被创造，当最小的干扰能产生各种各样的sublattice模式时。原始格子的三种不同类型被用来表明孤立的平方，在二维的光超点阵，其模式能被调节极化动态地操作的三角形、六角形的sublattice结构，频率，和激光横梁的紧张。另外，我们建议改变相对阶段在sublattices调整通道振幅的方法。我们的配置提供唯一的机会在交叉形成的格子学习粒子纠纷井并且在异国情调的格子几何学实现特殊的量逻辑门。

简介：VegetativecellsofPorphyrayezoensisareisolatedwithseasnailenzymeandculturedonthesolidifiedagarmedium.Theresultsofexperimentsshowthattheisolatedcellscansurvive,divideandregeneratewellonthemediumsolidifiedwithagar.Thefirstdivisiononthesolidmediumstartsafter7days'culture,4dayslaterthantheliquidculture.Thesurvivalrateofisolatedcellsis71.3%onthesolidmedium,lowerthanthe86.2%ofthatinseawater.Thalli,thalloids,conchocelis,spermatangiaandmulticellularmassesaredevelopedonthesolid/mediuminthefirstmonth,slowlybutnormally.Spermatangiasacsdisappearwithin4weeks.Withoutaddingnutrientliquidontothesurfaceofsolidmediumorinjectingseawaterundertheagarlayerinordertokeepmoisture,thethalliandcellgroupsreleasemonosporestoformnewthalliinsteadofenlargingtheirareasafter5weeks'culturing.Somemonosporesregeneratenewthalli.Othermonosporeslosetheirpigmentsandminimizetheirvolumeanddividequicklytoformlightpinkcalli.After16weeks,numerouscallicanbeseenonthesolidmediumandafter24weeks'culturing,almostonlycalliandconchoceliscanbeseen.Ifthecalliareimmersedinseawater,themonosporesarereleasedandmaydevelopintoyoungthallus.

简介：Bridgeseismicisolationstrategyisbasedonthereductionofshearforcestransmittedfromthesuperstructuretothepiersbytwomeans:shiftingnaturalperiodandearthquakeinputenergyreductionbydissipationconcentratedinprotectiondevices.Inthispaper,astochasticanalysisofasimpleisolatedbridgemodelfordifferentbridgeanddeviceparametersisconductedtoassesstheefficiencyofthisseismicprotectionstrategy.Toachievethisaim,asimplenonlinearsofteningconstitutivelawisadoptedtomodelawiderangeofisolationdevices,characterizedbyonlythreeessentialmechanicalparameters.Asaconsequenceoftherandomnatureofseismicmotion,aprobabilisticanalysisiscarriedoutandthetimemodulatedKanai-Tajimistochasticprocessisadoptedtorepresenttheseismicaction.TheresponsecovarianceinthestatespaceisobtainedbysolvingtheLyapunovequationforastochasticlinearizedsystem.Afterasensitivityanalysis,thefailureprobabilityreferredtoextremedisplacementandthemeanvalueofdissipatedenergyareassessedbyusingtheintroducedstochasticindicesofseismicbridgeprotectionefficiency.Aparametricanalysisforprotectivedeviceswithdifferentmechanicalparametersisdevelopedforaproperselectionofparametersofisolationdevicesunderdifferentsituations.

简介：Inthispaper,anewapproachofpatternrecognitionfortoneclassificationofPutonghuaWhichisim-portantforspeechrecognitionofPutonghuaisdiscribed.Inthismethod,fourparametersofthefundamen-talfrequencytrajectoryareselectedbasedonalargenumberofstatisticalexperiments.ItisassumedthatthefourparameterssatisfymultidimensionalGaussiondistributionandanon-Euclideandistancefunctionforeachtoneclassisderivedaccordingtotheruleofminimumprobabilityofcalssificationerror.theoptimaldecisionresultsareobtainedinasenseofstatistics.Itisprovedthatthismethodprovidesverysatisfactoryresultsbytheexperimentsforspeaker-independenttoneclassificationofPutonghua.

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简介：Theobjectiveofthisstudyistoidentifysystemparametersfromtherecordedresponseofbaseisolatedbuildings,suchasUSChospitalbuilding,duringthe1994Northridgeearthquake.Fullstatemeasurementsarenotavailableforidentification.Additionally,theresponseisnonlinearduetotheyieldingofthelead-rubberbearings.Twonewapproachesarepresentedinthispapertosolvetheaforementionedproblems.First,areducedorderobserverisusedtoestimatetheunmeasuredstates.Second,aleastsquarestechniquewithtimesegmentsisdevelopedtoidentifythepiece-wiselinearsystemproperties.Theobserverisusedtoestimatetheinitialconditionsneededforthetimesegmentedidentification.Aseriesofequivalentlinearsystemparametersareidentifiedindifferenttimesegments.Itisshownthatthechangeinsystemparameters,suchasfrequenciesanddampingratios,duetononlinearbehaviorofthelead-rubberbearings,arereliablyestimatedusingthepresentedtechnique.Itisshownthattheresponsewasreducedduetoyieldingofthelead-rubberbearingsandperiodlengthening.

简介：TostudythegeneticcharacterizationoffourstrainsofBorreliaburgdorferiisolatedinChina.PCRtechniquewasusedtoamplifythe5S-23SrRNAintergenicspacerDNAfromthewholecellularDNAofisolatedGXLD-4,9,18andChang14,andthentheamplifiedproductswereclonedintoplasmidpGEM-TEasyandsequenced.Itwasfoundthatthe5S-23SrRNAintergenicspacerDNAofthefourisolateswas242bp,revealingthenucleotidesequenceidentityofmorethan99%.ThefourisolateshadhighersequenceidentifywithBorreliavalaisianathanwithothergeneticgroups.ThesefourisolatesmostlikelybelongtoBorreliavalaisianagenomicgroup.

简介：从辽宁新民产蛇床Ｃｎｉｄｉｕｍｍｏｎｎｉｅｒｉ果实中分离鉴定出８个化合物，分别为２′乙酰白芷素（２′ａｃｅｔｙｌａｎｇｅｌｉｃｉｎ，８）、欧山芹素（ｏｒｏｓｅｌｏｎｅ，１）、β谷甾醇（βｓｉｔｏｓｔｅｒｏｌ，２）、哥伦比亚内酯（ｃｏｌｕｍｂｉａｎａｄｉｎ，３）、佛手柑内酯（ｂｅｒｇａｐｔｅｎ，４）、Ｏ乙酰基哥伦比亚甙元（Ｏａｃｅｔｙｌｃｏｌｕｍｂｉａｎｅｔｉｎ，５）、Ｏ乙酰异蛇床素（ｃｎｉｆｏｒｉｎＡ，６）和爱得尔庭（ｅｄｕｌｔｉｎ，７）。其中化合物８为一新化合物，化合物１系首次从该植物中分得。

简介：AIM:Tocomparethecornealparametersofchildrenwithcongenitalisolatedgrowthhormonedeficiencyandhealthysubjects.METHODS:Inthiscross-sectional,prospectivestudy,50caseswithgrowthhormone(GH)deficiencytreatedwithrecombinantGHand71healthychildrenunderwentacompleteophthalmicexamination.Thecornealhysteresis(CH),cornealresistancefactor(CRF),Goldmann-correlatedintraocularpressure(IOPg)andcorneal-compensatedintraocularpressure(IOPcc)weremeasuredwiththeOcularResponseAnalyzer(ORA).Centralcornealthickness(CCT)wasmeasuredbyaultrasonicpachymeter.RESULTS:Themeanagewas13.0±3.0yearsintheGHdeficiencygroupconsistingof21femalesand29malesand13.4±2.4yearsinthehealthychildrengroupconsistingof41femalesand30males.Therewasnostatisticallysignificantdifferencebetweenthegroupsforgenderorage(Chi-squaretest,P=0.09;independentttest,P=0.28,respectively).ThemeandurationofrecombinantGHtherapywas3.8±2.4yinthestudygroup.ThemeanCH,CRF,IOPgandIOPccvalueswere11.0±2.0,10.9±1.9,15.1±3.3,and15.1±3.2mmHgrespectivelyinthestudygroup.Thesamevalueswere10.7±1.7,10.5±1.7,15.2±3.3,and15.3±3.4mmHgrespectivelyinthecontrolgroup.ThemeanCCTvalueswere555.7±40.6,545.1±32.5μminthestudyandcontrolgroupsrespectively.TherewasnostatisticallysignificantdifferencebetweenthetwogroupsforCH,CRF,IOPg,IOPccmeasurementsorCCTvalues(independentt-test,P=0.315,0.286,0.145,0.747,0.13respectively).CONCLUSION:OurstudysuggeststhatGHdeficiencydoesnothaveaneffectonthecornealparametersandCCTvalues.ThisobservationcouldbebecauseofthedurationbetweenthebeginningofdiseaseandthediagnosisandbeginningofGHtherapy.

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简介：AbstractCommon or external iliac artery injury due to blunt trauma is unusual without an associated pelvic fracture. Here we report on a 62 years old man that sustained left external iliac artery thrombosis due to blunt trauma following fall from motorbike. There was no immediate circulatory compromise. Contrasted CT of abdomen revealed an associated left lower abdominal wall traumatic hernia. The iliac artery was intervened with an endovascular stent to restore luminal flow and the hernia was repaired electively. The entire clinical course and management dilemma are described in this article.

简介：以便在纵的方向在最相反的负担下面学习地震地孤立的桥的动态表演，为在纵的方向的车辆braking的一个动态方程被建立。一四或fiveorderRunge-Kutta方法被采用在braking力量下面获得一个车轮集合的时间历史反应。二次的discretization方法然后被用来在车辆braking力量下面把这时间历史转变成braking和一个结构的固定节点，和地震地孤立的桥的动态反应分析的弯曲力量时间历史用ANSYS被执行，一个通用有限元素分析软件。根据结果，地震隔离设计在墩之中导致braking力量的更合理的分布；车辆braking力量上的起始的braking速度的影响是可以忽略的；第一个车轮给了叶子桥的地点是最相反的停车地点；适用根据典型设计方法构造了的一座地震隔离桥在braking力量下面进入一个收益阶段，当当隔离时期被扩大，在墩的底部的砍的力量衰退时；当适用的地震隔离的收益排水量是不到5公里，收益力量比braking力量大时，设计要求能被满足。

简介：Westudytheflowofadensity-stratifiedfluidpassingoveranisolatedobstacle,usingtowing-tankexperiments.OurspecialconcernistheresponseoftheflowwithdifferentFroudenumberspassingoverathree-dimensionalobstacle.Aseriesofexperimentsofthestratifiedrotatingflowpassingoveranisolatedobstaclewascarriedoutwiththetowering-tankcontrolledbythesimilaritylawsanddynamicnon-dimensionparameters.TheseexperimentsshowthattheFroudenumberisaveryimportantparameter,andtheleewaveandtheeddystructureexperimentsshowthattheFroudenumberisaveryimportantparameter,andtheleewaveandtheeddystructureappearsimultaneouslyunderanappropriateconditions.Theeffectofrotationontheleewaveismainlytochangewaveamplitude,particularlytorestrainthedevelopmentoftheleewaveandtopromotetheformationofaneddy.