简介:The"ShanghaiFive"mechanismwasborninApril1996whentheRepublicofKazakhstan,thePeople’sRepublicofChina,theKyrgyzstanRepublic,theRussianFederationandtheRepublicofTajikistanheldasummitmeetinginShanghai.China.Thereaftertheyholdsummiteveryyearandeachofthemplayhostinturn.TheDushanbeSummitofJuly5,2000wastheirfifthmeeting.AfterfivesummitsfiveheadsofstateextensiveIyexchangedViewsofcommonconcern,and
简介:InWutheringHeights,HeathcliffandHaretonaretechnicallyenemiesbuttheysharemanysimilarities,suchastheirgrowingenvironment,feelingofinferioritycomplex,andtheirintensivepersistenceinlovefortheirbeloved.Themajordifferencebetweenthemistheattitudetowardsrevengeandtolerance.Depictingthesimilarityanddifferencebetweenthetwocharactersthatstartswiththesamefatebutendswithcompletelydifferentconsequence,EmilyBronteindicatesthekarmathatavengerwillsufferfromtheevilconsequencecommittedbyhimselfandtoleranceisthetruevirtue.
简介:Withthediscouraging,andhorrifyingdescriptions,ConradandGoldingunanimouslypresenttheuniversalsubjectmatterthatathisheart,manisanevil,vicious,and“fallen”being.Furthermore,humanbeingisjustsusceptibletohisownsinisternature.BothHeartofDarknessandLordoftheFliesimplythateverymanhasanevilheartofdarknesswhichismoreoftenthannotdrownedoutbytheglowofcivilization.
简介:AbstractSialendoscopy is a minimally invasive technique that facilitates the diagnosis and treatment of sialolithiasis. This case series presents the novel use of sialendoscopy to treat sialodocholithiasis in six patients with a non-functional or surgically absent submandibular gland by a single surgeon at the University of Pennsylvania Health System between March 2013 and December 2019. The four female and two male patients had a median age of 56 years and mean follow-up of 16.2 months (range 1-44.5). All stones were successfully removed using sialendoscopy, and in 5 patients a combined approach was utilized. All patients remain asymptomatic at last clinical follow-up. We conclude that sialendoscopy is a viable, minimally invasive method for managing sialodocholithiasis in patients with prior submandibular gland excision or atretic gland. It is also useful as an assistive tool when approaching complex transcervical or transoral procedures in previously instrumented patients.
简介:Onthesocialnetworkplatform,complaintsaboutthepublicpolicyformulationandimplementationissuesariselargely.Throughtheinformationaggregation,frequentinteraction,word-of-mouthandemotionalresonanceononlinesocialnetwork,theseinformationwillleadtotheoutbreakofthenetworkcomplaints.Itbringsdifficultiesandchallengesinpublicmanagement.Chinaisunderaperiodofsocialtransformation,andtherearevariousproblemsandcontradictions.Emergencycaneasilyarousegroupcomplaintsononlinenetwork,anditwillleadtonetworkpublicopinionthroughinducingsocialemotionalresonance,whichisharmfultosocialsecurityandstability.Thispaperhasbuilttheevaluationindexsystemfromfourdimensionswithcomplainttext’squality,transmissiontimeliness,userinteractiondegreeandemotionalresonanceexcitedbyemergency.Then,weestablishthedynamicinfluencemeasuremodelofonlinenetizenscomplaintthemebasedonanentropyweightmodel.ThemeasuremodelisprovedtobereasonableandeffectivebytheempiricalresearchofSinaWeibodata.Themodelcaneffectivelysolvethemeasureproblemofgroupcomplaintsinfluencewhentheemergenciesarousesocialemotionalresonance.Ithasimportanttheoreticalsignificanceandpracticalvalueforpublicpolicydecision-makeronlisteningtoonlinegroupcomplaints,understandingpublicopinion,andmakingpublicpolicy.
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简介:translational以后修正对蛋白质稳定性并且到蛋白质活动的调整中央。蛋白质修正的各种各样的类型例如phosphorylation,methylation,acetylation,myristoylation,glycosylation,和ubiquitination,被报导了。在他们之中,ubiquitination把自己与其它区分开来因为大多数ubiquitinated蛋白质为降级被指向到26Sproteasome。ubiquitin/26Sproteasome系统在房间组成主要蛋白质降级小径。在最近的年里,在众多的真核细胞的细胞的函数的控制的ubiquitination机械的重要性逐渐地被欣赏了。增加E3ubiquitinligases和他们的底层的数字,包括许多必要细胞的管理者被识别了。过去的几年里的研究表明了ubiquitination系统为大量植物是重要的发展过程和回答到不能生活、关於生命的压力。这评论从在植物微生物相互作用起重要作用的植物和病原体在联系ubiquitination的蛋白质的功能的分析讨论最近的进展。
简介:摘要