摘要
Theworldisexperiencingagingofitspopulation.Age-specificincidenceratesofcancerarehigherandcancerisnowrecognizedasapartofaging.Treatingolderpatientscanbechallenging.Theclinicalbehaviorofsometumorschangeswithageandtheagingprocessitselfbringsphysiologicalchangesleadingtodeclineinthefunctionoforgans.Itisessentialtoidentifythosepatientswithlongerlifeexpectancy,potentiallymorelikelytobenefitfromaggressivetreatmentvs.thosethataremorevulnerabletoadverseoutcomes.Aprimarydeterminationwhenconsideringtherapyforanoldercancerpatientisapatient'sphysiologic,ratherthanchronologicage.Inordertodifferentiateamongstpatientsofthesameage,itisusefultodetermineifapatientisfitorfrail.Frailolderadultshavemultiplechronicconditionsanddifficultiesmaintainingindependence.Theymaybemorevulnerabletotherapytoxicities,andmaynothavesubstantiallastingbenefitsfromtherapy.Geriatricassessment(GA)maybeusedasatooltodeterminereversibledeficitsanddevisetreatmentstrategiestomitigatesuchdeficits.GAisalsousedintreatmentdecisionmakingbyclinicians,helpingtoriskstratifypatientspriortopotentiallyhigh-risktherapy.AnimportantpracticalaspectofGAisthefeasibilityofincorporatingitintoabusyoncologypractice.KeyconsiderationsinperformingtheGAinclude:availableresources,patientpopulation,GAtoolstouse,andwhowillberesponsibleforusingtheGAresultsanddevelopcareplans.ChallengesinimplementingGAinclinicalpracticewillbediscussed.
出版日期
2015年04月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
