Mild to moderate hypothermia:the hope for improving outcome of severe head injured patients

(整期优先)网络出版时间:2001-01-11
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Traumaticbraininjury(TBI)isamajorpublichealthproblemthroughouttheworld.Morethan400000patientswithTBIintheUnitedStatesofAmericaandmorethanamillionpatientswithTBIinChinaareadmittedtohospitaleveryyear.HeadtraumaisalsoNo.1killerofyoungpeopleinthedevelopedcountriesaswellasinsomedevelopingcountries.Unfortunately,theoutcomeofpatientswithsevereTBIisstillpoorallovertheworld.ThemortalityofsevereTBIpatients(GCS3-8)inmajorityofhospitalsisover30%andverysevereTBIpatients(GCS3-5)isover80%withonly15%functionalrecovery.1,2However,recentadvanceincerebralprotectionbymild(35-33℃)tomoderatehypothermia(32-30℃)iscertainlyencouraging,whichbringsneurosurgeonsthehopetoimprovetheoutcomeofsevereheadinjuredpatients.