简介:BACKGROUND:Asaginginelderlypeople,theirbraintissuehasdegenerationandbrainatrophyofdifferentseverity,andthevolumeofcranialcavityisrelativelyenlarged,ithasgreatercompensatoryabilitytothespaceoccupyinglesion,anditisdifficulttodetectthemeningiomabecauseitgrowstoexpandslowly,thetumorlocatesinnon-functionalregion,andthereareatypicalsymptomsanddeficiencyoflocalizationsigns.OBJECTIVE:Toinvestigatetheclinicopathologicfeaturesofsenilemeningiomas.DESIGN:Aretrospectiveanalysis.SETTING:AffiliatedHospitalofHebeiUniversity.PARTICIPANTS:Forty-nineelderlypatientswithmeningiomawereselectedfromtheDepartmentofNeurosurgery,AffiliatedHospitalofHebeiUniversityfromMay1999toMarch2005,including15malesand34females,60-74yearsofage,andtheywerealldiagnosedbyCTandMRI.METHODS:ThesitesoftumorswereidentifiedbyCTandMRIexaminationsinallthepatients.Thetumorswerepartiallyortotallyresectedaccordingtotheirownconditions.Thetypesoftheresectedtumorwerepathologicallyobserved.Theconditionsofpostoperativerecoverywereobservedafter1,3and6months,andwithoutnewneurologicaldysfunctionorcomplicationwasconsideredasgoodoutcome.MAINOUTCOMEMEASURES:①Sitesandpathologicaltypesofthetumor;②Postoperativeoutcomesandcomplications.RESULTS:Allthe49patientswereinvolvedintheanalysisofresults.①Thetumorshadwidedistributionswithamainlocationinbrainconvexity.Amongthe49casesofmeningioma,therewere25casesoffibrocystictype,12casesofmeningothelialtype,6casesofpsammomatoustype,4casesofangiomatoustypeand2casesofmicrocystictype.②Amongthe49patients,35hadgoodoutcome,8hadself-careability,4requiredcarebyothers,2(4.1%)diedpostoperatively.Nolong-termcomplicationrelatedtotheoperationwasobservedduringthefollow-uppostoperatively.CONCLUSION:Meningiomahasamainlocationinbrainconvexity,andits
简介:Inflammatorydemyelinatingpseudotumorusuallyoccursinthebrainandrarelyoccursinthespinalcord.Onimaging,inflammatorydemyelinatingpseudotumorappearsverysimilartointramedullarytumorssuchasgliomas.Itisoftenmisdiagnosedasintramedullarytumorandsurgicallyresected.Inviewofthis,theclinicalandmagneticresonanceimagingmanifestationsandthepathologicalfeaturesof36casesofinflammatorydemyelinatingpseudotumorinthespinalcordwereretrospectivelyanalyzedandsummarized.Mostofthesecasessufferedfromacuteorsubacuteonsetandexhibitedasensorimotordisorder.Amongthem,sixcasesweremisdiagnosedashavingintramedullarygliomas,andinflammatorydemyelinatingpseudotumorwasonlyidentifiedandpathologicallyconfirmedaftersurgicalresection.Lesionsinthecervicalandthoracicspinalcordwerecommon.Magneticresonanceimagingrevealededemaandspace-occupyinglesionstovaryingdegreesatthecervical-thoracicjunction,withapredominantfeatureofnon-closedrosette-likereinforcement(open-loopsign).Pathologicalexaminationshowedperivascularcuffingofpredominantlydenselymphocytes,anddemyelinationwasobservedinsixofthemisdiagnosedcases.Theseresultssuggestthattumor-likeinflammatorydemyelinatingdiseaseinthespinalcordisakindofspecialdemyelinatingdiseasethatcanbecategorizedasinflammatorypseudotumor.Thesesolitarylesionsareeasilyconfusedwithintramedullaryneoplasms.Patchyornon-closedreinforcement(open-ringsign)onmagneticresonanceimagingisthepredominantpropertyofinflammatorydemyelinatingpseudotumor,andinflammatorycellinfiltrationanddemyelinationareadditionalpathologicalproperties.