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  • 简介:AbstractMetabolic (dysfunction) associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease, is the most common cause of chronic liver disease worldwide. Many risk factors contribute to the pathogenesis of MAFLD with metabolic dysregulation being the final arbiter of its development and progression. MAFLD poses a substantial economic burden to societies, which based on current trends is expected to increase over time. Numerous studies have addressed various aspects of MAFLD from its risk associations to its economic and social burden and clinical diagnosis and management, as well as the molecular mechanisms linking MAFLD to end-stage liver disease and hepatocellular carcinoma. This review summarizes current understanding of the pathogenesis of MAFLD and related diseases, particularly liver cancer. Potential therapeutic agents for MAFLD and diagnostic biomarkers are discussed.

  • 标签: Metabolic (dysfunction) associated fatty liver disease Liver disease Liver cancer
  • 简介:"TryEverything"是迪士尼3D动画片《疯狂动物城》(Zootopia)的主题曲,节奏感强,歌词更是十分励志。这首歌由拉丁女歌手Shakira演唱,她出生于哥伦比亚,早期以演唱西班牙语歌为主,后为与英语乐坛接轨开始演唱英语歌曲。Shakira最脍炙人口的歌曲要属她为2010年南非世界杯演唱的官方主题曲《非洲时刻》(WakaWaka)。这首"TryEverything"延续了她一贯的拉丁曲风节奏欢快又带有一些异域风情。片中的动物城是一个现代化的动物大都市,在这里,各种动物都生活在一

  • 标签: 一切皆有可能 TRY Everything 英语歌曲 迪士尼 谓语动词
  • 简介:一天,一个非常富有的广州家庭到乡下旅游,爸爸想让儿子看一看乡下人有多么贫穷,就在一个穷困的农家住了一天一夜。当他们回到城里时,爸爸问儿子:“亲爱的儿子,这次旅行感觉怎么样?”

  • 标签: 初中 英语 双语阅读 对照读物
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