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简介:Inordertoinvestigatetherelationshipbetweenthetraceelementsandthecharacteristicsoftheoysters,weanalyzedthetraceelementspresentinthegermplasmofoystersfromdifferentproducingareasintheJiaozhouBay.Theelementfingerprintswereestablishedtoreflecttheelementalcharacteristicsoftheoysters.Concentrationpatternsoftheelementsweredecipheredbyprinciplecomponentanalysis(PCA)andhierarchicalclusteranalysis(HCA).ThesixregionswerediscriminatedwithaccuracyusingHCAandPCAbasedontheconcentrationof16traceelements.Theelementswereviewedascharacteristicelementsoftheoystersandthefingerprintsoftheseelementscouldbeusedtodistinguishthequalityoftheoysters.
简介:150casesofprolapseoflumbarintervetebraldiscwererandomlydividedintotreatmentandcontrolgroups.80casesintreatmentgroupweretreatedwithcombinationofacupuncture,oraladministrationofChinesemedicinalherbs,traction,point-injectionandintravenousdripofenergydehydrationmixture;70casesincontrolgroupweremanagedbycombinationofacupuncture,oraladministrationofherbalmedicines,traction,acupoint-injection(withoutenergydehydrationmixture).Theresultsshowedthatthecurativerateandthetotaleffectiverateofthetreatmentgroupwere91.25%and98.75%separately,whilethoseofthecontrolgroup62.86%and92.86%respectively.Comparisonofthecurativeratebetweenthe2groupsshowedaremarkablesignificance(P<0.01).TheobservationdemonstratedthatcombinedtreatmentofprolapseoflumbarintervertebraldiscwithtraditionalChineseandWesternmedicineisaneffectiveapproach.
简介:Acutemyeloidleukemia(AML)isageneticallyheterogeneousmyeloidmalignancythatoccursmorecommonlyinadults,andhasanincreasingincidence,mostlikelyduetoincreasingage.PrecisediagnosticclassificationofAMLrequiresclinicalandpathologicinformation,thelatterincludingmorphologic,immunophenotypic,cytogeneticandmoleculargeneticanalysis.RiskstratificationinAMLrequirescytogeneticsevaluationasthemostimportantpredictor,withgeneticmutationsprovidingadditionalnecessaryinformation.AMLwithnormalcytogeneticscomprisesabout40%-50%ofallAML,andhasbeenintensivelyinvestigated.Thecurrentlyused2008WorldHealthOrganizationclassificationofhematopoieticneoplasmshasbeenproposedtobeupdatedin2016,alsotoincludeanupdateontheclassificationofAML,duetothecontinuouslyincreasingapplicationofgenomictechniquesthathaveledtomajoradvancesinourknowledgeofthepathogenesisofAML.ThepurposeofthisreviewistodescribesomeoftheserecentmajoradvancesinthediagnosticclassificationandriskstratificationofAML.
简介:并且它符合人生三定律中的平衡稳定定律以及生存发展定律按照人生三定律之平衡稳定定理,对当事人双方都能得到人生平衡,对当事人双方都能得到人生平衡
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简介:Type2cytokinesareusuallypredominantintumorpatientsandassociatedwithtumorprogression.Toexplorewhetherreversingoftype2predominancecouldbeapromisingstrategyintumorimmunotherapy,PBMCsof35lungcancerpatientsand19healthysubjectswerepreparedandsubjectedtobeexaminedforcytokinesecretionandgeneexpression.Tetra-Methylpyrazine(TTMP),extractedfromatraditionalChinesemedicinalherbwhichhasbeenusedinclinictoreversetheTh2statusofcancerpatientsinChina,wasaddedtoPBMCculture.DeterminedbyRT-PCR,thepositivepercentagesofmRNAexpressionoftype1cytokines(8.6%forIFN-γand11.4%forIL-2)werelowerthanthoseoftype2cytokines(71.4%forIL-4,60%forIL-6and80%forIL-10)inpatients'PBMCs.Thepotentialofgeneexpressing(measuredasrelativeintensitytotheratioofβ-actin)inthepatientsfortype1cytokineswasalsoinalowlevel(0.111forIFN-γ,0.119forIL-2)incomparisonwitharelativehighlevelfortype2cytokines(0.319forIL-4,0.303forIL-6and0.377forIL-10).Meanwhile,bothpositivepercentageandrelativeintensityofgeneexpressionwerelowerforatype1cytokine-relatedtranscriptionfactorT-bet(31.4%and0.142,respectively)thanthosefortype2cytokine-relatedGATA3(85.7%and0.378,respectively).ThebloodserumlevelsofIFN-γandIL-2inthepatientswereslightlylowerbutnotsignificantlywhencomparedwithhealthycontrol.Incontrast,thelevelsIL-4andIL-6inpatientsweresignificantlyhigherthanthoseinhealthysubjectsbyELISAanalysis.TTMPcouldenhancesupernatantconcentrationandgeneexpressionlevelsofIFN-γ,IL-2andT-bet,butreducedthoseoftype2cytokines.Theseresultsdemonstratethatthelungcancerpatientshadapredominantexpressionoftype2cytokinesandTTMPcouldreversethetype2dominantstatus,whichmightofferanalternativetherapeuticregimeforlungcancerpatients.Cellular&MolecularImmunology.2004;1(1):63-70.
简介:PulsediagnosisplaysavitalroleinTraditionalChineseMedicine(TCM).Toextracteffectiveandproperfeaturesfromthewrist-pulse-signalsisacrucialstepfortherecognitionandclassificationofthepulsesignals.Althoughtheanalysisinthetimedomainisalsoveryeffectiveforalotofpulsetypes(SHUetal.,2007),thefrequencyandtime-frequencyanalysisareusuallyusedintheliterature(YANetal.,2005;YUEetal.,2006)becausethepulsesignalsarenon-stationaryandnon-periodictimeseriesinthepathologicalstates.Inrecentyears,anewtime-frequencyanalysismethod,Hilbert-HUANGTransformproposedby
简介:INTRODUCTIONInChina,liverfibrosisinmostpatientsresultedfromthevirusesofhepatitisB.Bothanti-virusandanti-fibrosisshouldbeconsideredindesigningaprogramforthetreatmentofliverfibrosis.Therefore,40casesofliverfibrosisduetohepatitisBweretreatedbyusingIFN-α1andtraditionalmedicinalpreparationsfromFebruary1994toApril1996.Goodcurativeeffectwasachieved.
简介:BasedonthefuzzycharacteristicofthepulsestateandsyndromesdifferentiationthinkingmodeofTCM,aninformationfusingrecognitionmethodofpulsestatesbasedonSFNN(StochasticFuzzyNeuralNetwork)ispresentedinthispaper.Withthelearningabilityinparametersandstructure,SFNNfusesthemeasurementinformationofthreepulse-statesensorsdistributedinCun,Guan,andChilocationofbodyforthepulsestaterecognition.Theexperimentalresultsshowthatthepercentageofcorrectrecognitionwithnewmethodishigherthanthatbysingle-datarecognitionone,withfeweroff-linetrainnumbers.
简介:Objective:TostudytheeffectoftraditionalChinesemedicineantiviralcapsulesinthetreatmentofgenitalherpes.Methods:Usingfemaleguineapiggenitalherpesastheanimalmodel,thisstudyusedoraladministrationoftwoformulationsofantiviralcapsules(AC)andobservedtheeffectonvaginalHSV-2titersandvulvarsymptoms.CellcultureswerealsousedtoexaminethedirectinactivationofHSV-2bytheantiviralcapsulesandthesuppressionofHSV-2viathreedrugadministrationmethods.Results:Therewasnosignificantdifferenceofmeanvaginalvirustitersbetweentheantiviralcapsulegroupsandthatofthepositiveacyclovir(ACV)control(P>0.05).Meanvulvarsymptomscoresofthetwoantiviralcapsulegroupswerealsosignificantlylowerthanthatofthesalinenegativecontrolgroupondays2,3,5,7and8(P<0.05)andsimilartothatoftheACVcontrol(P>0.05).CellcultureshowedtheminimuminhibitoryconcentrationsofantiviralcapsulesNo.1andNo.2were0.390625mg/mland1.5625mg/ml,respectively.Conclusion:ThetraditionalChinesemedicineantiviralcapsuleshadsuppressiveeffectsonHSV-2inbothanimalmodelGHandinvitrocellculture.
简介:Complicationsaremorefrequentinelderlypatientswithcoronaryheartdisease(CHD),suchasimpairedglucosetoleranceandconstipations.Itisalwaysdifficulttocurethesecomplicationsinclinicalpractice.Inthiscasewehadsuccessfullycuredaneighty-threeyearsoldmanwithCHDcomplicatingimpairedglucosetoleranceandconstipationbyintegratedChinese-Westernmedicine.