简介:Despitethehnpactofhighly-activemltiretroviraltherapy(HAART),manifestedasmarkedreductionsintheincidenceofopwrtunistieinfectionsinthelast5,years,respiratoryproblemsstillconstituteamajorburdenofdiseaseinthoseinfectedwithHIV.ReasonsforthisincludethelimitedavailabilityofHAART.worldwide,thefailureofsustainedviralsuppressioninupto50%ofpatientstakingHAART,failureofprophylaxisforspecificopportunisticinfectiorrs,andanincreasingnumberofpatientspresentingwithpreviouslymldiagnosedadvancedHIVinfection.
简介:AIDSassociatedmalignancies(ARL)isamajorcomplicationassociatedwithAIDSpatientsuponimmunosuppression.Chronicallyimmunocompromisedpatientshaveamarkedlyincreasedriskofdevelopinglymphoproliferativedisease.Intheeraofpotentantiretroviralstherapy(ARV),themalignantcomplicationsduetoHIV-1infectionhavedecreasedindevelopednationswhereARVisadministered,butstillposesamajorproblemindevelopingcountrieswhereHIV-1incidenceishighandARVisstillnotyetwidelyavailable.EveninARVtreatedindividualsthereisaconcernthattheprolongedsurvivalofmanyHIV-1carriersislikelytoeventuallyresultinanincreasednumberofmalignanciesdiagnosed.MalignanciesthatwerefoundtohavehighincidenceinHIV-infectedindividualsareKaposi'ssarcoma(KS),Hodgkin'sdisease(HD)andnon-Hodgkin'slymphoma(NHL).TheincidenceofNHLhasincreasednearly200foldinHIV-positivepatients,andaccountsforagreaterpercentageofAIDSdefiningillnessintheUSandEuropesincetheadventofHAARTtherapy.TheseAIDSrelatedlymphomasaredistinctfromtheircounterpartsseeninHIV-1seronegativepatients.ForexamplenearlyhalfofallcasesofARLareassociatedwiththepresenceofagammaherpesvirus,EpsteinBarrvirus(EBV)orhumanherpesvirus-8(HHV-8)/Kaposi'ssarcomaassociatedherpesvirus(KSHV).ThepathogenesisofARLsiscomplex.B-cellproliferationdrivenbychronicantigenemiaresultingintheinductionofpolyclonalandultimatelymonoclonallymphoproliferationmayoccurinthesettingofsevereimmunosuppression.
简介:Objective:ToincorporatestudentsandotherlocalcommunitypartnersincreatingacollaborativeNanjingWorldAIDSDayexhibition.Background:StigmaanddiscriminationcontinuetocomplicateeffectiveWorldAIDSDayactivitiesinChina.IncludingforeignstudentsinWorldAIDSDaycampaignsbroadensthepotentialChineseaudienceaswellasmakingthegovernment'sAIDSpoliciesmoretransparent.Methods:Inordertobroadenthepotentialaudience,relevantmedia(television,radio,newspaper)werenotifiedofthe2003NanjingWorldAIDSDayExhibition.TheexhibitionrepresentedauniquecollaborationbetweenNanjingUniversityandtheChineseNationalCenterforSTDandLeprosyControl,dependingonforeignandChinesestudentsatseverallevels.Inaddition,closecontactsattheJiangsuProvincialHealthBureauhelpedtocoordinatelocalexpertsanddistributionofcondoms.Results:Thismulti-disciplinarycooperativeexhibitionwassuccessfullycompleted.Severalmajormediasourcescoveredtheevent.Conclusions:ThesuccessofthiscampaignsuggeststhatotherurbancitieswithsignificantforeignstudentpopulationscouldbenefitfromincludingforeignandChinesestudentsinfutureWorldAIDSDaycampaignactivities.
简介:DecemberfirstwasWorldAIDSDay.Lastyear,thecampaign(运动;活动)centeredonwomenandgirls.TheymadeupalmosthalfofallpeopleinfectedwiththevirusHIVthatcausesAIDS.AndH1Vwasspreadingfasteramongwomenthanmeninmostareasoftheworld.Thesefindings(发现)werefromtheyearlyreportbytheUnitedNationsandtheWorldHealthOrganization,aUNagency
简介:GreaterEfortstoCombatAIDSHIV-infectedpatientsandthosewithothersexualy-transmiteddiseases(STDs)haveincreaseddrasticalyinrece...
简介:DevelopingawidelyadaptableAIDSvaccineisthegoalofscientistswhofightagainstglobalproliferationofthedeadlydisease.NoW,somearefocusingtheirstudyonChina,believingthatthecountrymaybetheperfectpartnerforacollaborationinvaccineresearch.AninternationalAIDSvac...
简介:HIVisablood-bomevirustransmittedviasexualintercourseorpercutaneousexposuretoinfectedblood,orfromaninfectedmothertoherchildduringthebirthprocess.Followinginfection,thetimebeforeonsetofclinicaldiseasevariesfrommonthstoyears;thedurationisinfluencedbyage(therateofprogressionincreaseswithage)andHLAtype(A1,B8,DR3areassociatedwithrapidprogressionandB27withslowprogression),butnotbygenderorriskactivity.Althoughmostpatientsinitiallyhavenocharacteristicsymptoms,thereisusually(90%)agradualdeclineinimmunefunction.
简介:Overthepastyear,theLegalCounselingHotlineopenedbytheBeijingAizhixingHealthEducationInstitutehasreceivedmorethan200callsandactedasalawagentfor87cases.ProblemscoveredincludetheseekingoflegalaidsforcasesofAIDSinfectionbybloodtransfusionandtheuseofbloodproductsandforcasesofvirushepatitis,theprotectionofprivacyofAIDSpatients.
简介:Herfirstthoughtwastocommitsuicide.ButthreeyearsafterXiaShuqingfoundoutshewasHIVpositive,shelaughsandaddsthat,thankstocompensationfromthelocalgovernment,herannualfamilyincomehasnowdoubled.
简介:HenanProvinceinCentralChinaistakingthefightagainstHIV/AIDSclosertohomewith76officialspostedinvillagesseriouslyaffectedbythedeadlyvirus.Theofficials—dividedinto38pairs—arefrom38provincialgovernmentdepartments,suchasthehealthandfinancebureaux,willbestationedin38villagesforayear.TheystarttheirworkonFebruary18afterreceivingAIDSpreventiontraining.Thereareatleast10HIV/AIDSsufferersinthedesignatedvillagesandsomeofthemhaveupto400,saysGuoWeiqun,deputydirectorofthegeneralofficeofHenanHealthBureau.