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142 个结果
  • 简介:病人是有便血的一个33岁的人。结肠镜检查与流血揭示了分成小叶的梗节的息肉,在直径的大约40公里,在上升冒号。息肉有红、白的部件和一个马赛克模式。放大观察与扩大回合或卵形的地窟开始揭示了一个红崎岖表面部件,和光滑的白小瘤。内视镜的polypectomy被执行。标本的组织学的检查与膀胱的变化在薄板propria,平滑肌的增长,和增生的腺揭示了煽动性的肉芽组织。这息肉作为煽动性的myoglandular息肉(IMGP)被诊断。在上升冒号的由小叶片组成类型的IMGP是稀罕的。

  • 标签: 息肉 结肠镜检查 放大内窥镜检查法 息肉切除术 便血
  • 简介:目的:通过蛋白质组技术鉴定针刺抗哮喘血清中差异蛋白,明确针剌抗哮喘效应的物质基础。方法:采用蛋白质双向电泳技术,对针刺抗哮喘血清进行蛋白质组份差异分析,并对差异蛋白质点进行质谱鉴定。结果:双向电泳显示,与其它组相比,肾上腺切除哮喘模型针刺组血清与哮喘模型针刺组血清有一个明显深染的蛋白点(MW=44.1kD,PI=5.1),质谱结果为60S核糖体蛋白L13或假想蛋白FLJ32191;双向电泳显示,与其它组相比,肾上腺切除哮喘模型针刺组血清有两个高峰度蛋白点(MW=39.8kD,PI=4.9和MW=39.5kD,PI=5.0),质谱分析表明依次为锌指蛋白208、甲状腺激素受体相关蛋白;双向电泳显示,肾上腺切除哮喘模型针刺组血清中有两个明显区别于其他组的特有蛋白点(MW=17.3kD,PI〈4.5和16.9kD,PI〈4.5)。质谱分析表明依次为亲环蛋白A、锌指蛋白91。结论:针刺治疗哮喘,是整体调整的多靶点效应,与免疫调节、基因表达、蛋白质合成等密切相关。针刺应答蛋白质功能有待深入研究。

  • 标签: 针刺疗法 哮喘 电泳 蛋白质组 大鼠
  • 简介:Topreparemanganese-containingspinelsulfurtransferagentwithacidpeptization,ultrasonicwaveisusedforthefirsttimetomodifythestructureofsulfurtransferagentinthiswork.Minifixedbedreactorwasusedtoinvestigatetheeffectofultrasonicpower,timeandtemperatureonthestructureandoxidationadsorptionperformanceofsulfurtransferagentandtheadsorptionkineticsandmechanismofSO2wereanalyzed.SEM,TEM,XRDandN2adsorption-desorptiontechniqueswereemployedtocharacterizeandanalysethefunctionofsulfurtransferagent.Theresultsindicatedthatmanganese-containingspinelisakindofpromisingsulfurtransferagentandexhibitshighersulfurcapacityanddesulfurizationdegreeundertheselectedconditionsoftheultrasonicwavepowerof60%,andwiththetreatmentperiodfor3hatatemperatureof60°C.

  • 标签: 超声波功率 硫转移剂 吸附性能 结构 MN 固定床反应器
  • 简介:我们在经历了激进的前列腺切除术(RP)的病人之中根据前列腺癌症的clinicopathological特征调查了瘤参与(PTI)的百分比的预示的意义。没有任何neoadjuvant或辅助治疗,经历了在2003年9月和2008年3月之间的RP的534个病人的回顾的研究被执行。有各种各样的clinicopathological特征和生物化学的没有复发的幸存的PTI的协会经由uni-和multivariate分析被检验。multivariate模型的预兆的精确性与在曲线下面操作导出特征的区域的接收装置被估计。PTI被表明显著地与外科手术前的前列腺特定的抗原(PSA)被联系水平(P=0.001),病理学的格利森分数(P<;0.001),extraprostatic瘤扩展(P<;0.001),精囊侵略(P<;0.001)并且积极外科的边缘(P<;0.001)在univariate分析。当病人们被成层进疾病风险组时,PTI在低风险的组(P=0.033)然而并非中介之中仅仅是在multivariate分析的生物化学的没有复发的幸存的一个独立预言者--(P=0.287)或高风险的组(P=0.828)。PTI的增加显著地没增加分别地在彻底的病人(P=0.459)和低风险的组(P=0.268)之中为生物化学的没有复发的幸存的预言设计的multivariate模型的精确性。在结论,尽管PTI看起来比在有更高的风险疾病的那些之中是在有低风险的疾病的病人之中的一个更重要的预示的因素,总的来说,PTI不能提供在罐头已经经由确定的预示的因素被获得的以外的另外的预示的信息。

  • 标签: 前列腺癌 辅助治疗 风险 预后 疾病 肿瘤
  • 简介:Thisisareportofanonrandomizedcomparisonoftreatmentresultsof139patientswithstageIB,HAandproximalIIBcarcinomaoftheuterinecervixtreatedbyradiationaloneand113treatedwithacombinationofradiationandsurgery.Thefive-yeartumorfreeacturialsurvivalforthepatientswithstageIBeitherwithirradiationalone(RT)orcombinedwithsurgery(RS)wasapproximately87%.ForstageⅡthetumorfreeactuarialfive-yearsurvival79%withpatientsofRS,and76%withRT.Inthe113patientstreatedwithRStherewere18(16%).Inthe139patientstreatedbyRTtherewere18(13%)recurrencesofpelvic,4localrecurrences,11combinedwithparametrial,andfreeparametrialrecurrences.Therewasnosignificantdifferenceinthesurvivalandrecurrencerateofthepatientstreatedwitheithermethod.Majorcomplicationswerecomparableinbothgroups(RTapproximately25%andRSapproximately10%),but2/3ofthosecomplicationsrecoveredwithoutsequelae.Themostfrequentminor

  • 标签: ALONE uterine recurrence CERVIX comparable IRRADIATION
  • 简介:第二等的绿内障的长期的结果在回顾的学习包括了的一系列中国patients.METHODSThe与Ahmed绿内障阀门(AGV)由于眼色素层炎对待培植的AIMTo报告从经历了AGV培植的有uveitic绿内障的56个病人的67只眼睛。治疗的成功被定义为完成压力(IOP)从基线IOP在6和21公里Hg之间铺平与或没有另外的反绿内障药或最少20%减小的intraocular的病人。主要结果大小包括了IOP,在1点的绿内障药的数字,3,6,12,24,36,48并且在外科以后的60mo,外科的复杂并发症,最后的改正最好的视觉尖酸(BCVA),吗视觉地(VF)和网膜的神经纤维层(RNFL).RESULTSThe平均数后续是53.3灡?潬桲硥獩??

  • 标签: uveitic 绿内障 Ahmed 绿内障阀门 后续 中国人口
  • 简介:Thewriterhastreated30casesoftemporomandibulararticulardysfunctionsyn-dromewithonlyauricularpressingtherapy.Themethod:AseedofvaccariasegetalisisusedtotapetheAntitraticApexpointandtheShenmenpointofear,thenthepractitionerpressestheseedwithhandtoproducesensations,suchasdistension,numbness,heat,andalittlesweatingetc..Exchangtwosidesoftheearsalternatively.Thetreatmentisperformedonceeverytwoorthreedaysandthreetimesareconstitutedonecourse.Inoneorthreecourseswecanobtainthetherapeuticeffectivenessas50%cured,43%improvedand6.7%failed.

  • 标签: TEMPOROMANDIBULAR articulation DYSFUNCTION Auricular-point-pressing THERAPY Vaccaria
  • 简介:ObjectivesToanalyzethechangesofvasoactivesubstancesoriginatedfromendotheliuminpatientswithunstableanginapectoristreatedbymodifiedthrombolytictherapyandexplorethemechanismsofthedrugtotreatunstableanginapectoris.Methods120patientswithunstableanginapectoriswhowerenotwellresponsedtocommonmedicationwerestudied.TheirECGstresstestswereabnormalandtherewereischemicchangesinHolter.Urokinase300,000Uwasaddedin100mlnormalsalineandinjectedwithin30minonceadayfor3days.300mgaspirinwasadministratedadaybeforeandduringurokinaseapplications.Beforeandafterurokinasetreatments,endothelin-1,plasmatissueplasminogenactivatoranditsinhibitor-1weredetermined.ResultsComparedwithpretreatments,aftertreatments,theactivitiesoftissueplasminogenactivatorincreased,endothelin-1andtheinhibitor-1decreased.Thechangesweresignificant.ConclusionsModifiedthrombolytictherapycanregulatethevasoactivesubstancesoriginatedendotheliuminpatientswithunstableanginapectoris.Themajorsubstancesincludeendothelin-1,plasmatissueplasminogenactivatorandinhibitor-1.Thismechanismmaysuggestthaturokinasecantreatcoronaryheartdiseaseeffectively.

  • 标签: ANGINA PECTORIS IMPROVED THROMBOLYTIC therapy ENDOTHELIUM
  • 简介:Thermodynamiccalculation,SEM(scanningelectronmicroscopy),TEM(transmissionelectronmicroscopy),XRD(X-raydiffraction),phaseextraction,andchemicalanalysiswereemployedtostudythephasestabilityandphaseprecipitationinanewNi-Cr-Cobasesuperalloyheat-treatedat704and760℃foralongtime.Theresultsshowthattheprecipitatesofthisnewalloyheat-treatedatstandardannealingconditionandheat-treatedat704and760℃foratimeupto2000hareγ′,MC,M23C6,andM6C,andηphaseformsatgrainboundariesandinmatrixofsamplesheat-treatedat760℃aswell.Themassfractionsofγ′(+η),MC,M23C6,andM6Cinallsampleshavenolargechangeswithanincreaseinagingtime,butγ′precipitatesgrowobviously.Theγ′-to-ηtransformationinthesamplesheat-treatedat760℃tookplacewithincreasingagingtime.TheηprecipitatesformaWidmanstattenpattemandtheγ′phaseshaveremeltedpartlyinthesamplesheat-treatedat760℃.Thealloymaintainsabettermicrostructuralstabilityduringprolongedagingat704℃,butaworsemicrostructuralstabilityduringprolongedagingat760℃.

  • 标签: 微观结构 Ni-Cr-Co系 超耐热合金 热处理 热力学 沉淀物
  • 简介:Theutilizationofreclaimedwatercouldbeanefficienttooltoalleviatewaterscarcity,especiallyfordryriveraugmentation.However,itiscrucialtomonitorwaterqualitytoensuresafetytohumanhealthandtoavoidnegativeeffectsontheenvironment.ReclaimedwatersampleswerecollectedbimonthlyfromMaytoNovemberin2010inChaobaiRiver,andthephysiochemicalparametersweredetermined.Themainresultsareasfollows:Theparametersexceedingthethresholdvalueofthewaterguidelinesaremainlynutritionrelatedtonitrogenandphosphorus,whichareknowntoincreasetheriskofeutrophicationinsurfacewaters.Additionally,nitriteandnitratecanbedetrimentaltohumanhealth.ThemajorityoftheparametershaveapeakingconcentrationinMay,whereasotherseithershowsignificanttemporalvariationovertheentireperiodorremainrelativelyconstantinallfourmonths.Correlationanalysisshowsthatsomeparameters(pH,TandB)havenosignificantcorrelationwithothers,whereassignificantpositivecorrelationwasfoundforSrwithECandTDS,forCIwithTDS,forSi02withTPandforNO3-NwithTNandasignificantnegativecorrelationbetweenSO4andBa.Accordingtoprincipalcomponentanalysis,60.108%ofthetotaldataisrepresentedbydominantsolutes,andthesecondprincipalcomponentwithapercentageof31.876comprisesparametersrelatedtonitrogen.Subsequentclusteranalysisofparametersidentifiedfourgroups,whichrepresentdifferentcompositions,andsamplesinMaydifferfromothers.

  • 标签: WATER quality TREATED URBAN WASTEWATER WATER
  • 简介:对待热的激活的碳(TAC)上的元素的水银俘获用实验室规模被学习固定的床反应堆。TAC的能力被学习在N2和基线气体气氛下面执行Hg0俘获,普通的酸气体成分的效果个别地被评估避免源于多重部件的共存的复杂并发症。结果建议激活的碳(交流)上的功能的组(SFG)是的那表面对当酸气体不在时的Hg0俘获重要。同时,酸气体部件的存在在TAC戏上结合了有缺点的graphitic格子在有效Hg0的一个重要角色俘获。HCl的存在,NO2,并且显著地个别地不由于Hg0的异构的氧化在TAC上在基本气体提高Hg0俘获在有缺点的graphitic格子在TAC上在碳表面和催化作用上创造的酸的地点上。同样,SO2的存在在大约20%改进Hg0俘获。这改进多半在碳表面上由于催化作用由SO2在AC表面和元素的水银的氧化上源于硫组的免职。而且,当酸气体在烟道气体是在场的时,O2在Hg0氧化和俘获上展出synergistic效果。

  • 标签: 烟道气体 水银 激活的碳(交流)
  • 简介:Samplesofacobalt-basedalloythatunderwentasurfacetreatmentwereevaluated.Thesamples,whichwereobtainedbycastingalloyASTMF75,weregroundandpolishedononesideuntilamirrorfinishwasobtained.Thesampleswereencapsulatedinwollastonite(W)usinguniaxialpressure,treatedat1220℃for1handsubsequentlytemperedinwater.Thecharacterisationofthesampleindicatedthatpartoftheceramicencapsulatingmaterialwasmechanicallyincorporatedonthemetallicsurfacebygrowthoftheoxidelayerofthealloy.Afterthermaltreatment,aseriesofspecimensweresubmergedinasolutionwith5-foldsimulatedbodyfluid(5SBF)for3,5and21days.Characterisationbyscanningelectronmicroscopy(SEM),energydispersivespectroscopy(EDS)andX-raydiffraction(XRD)indicatednucleationandgrowthofahomogenouslayerofapatite,beginningonthethirddaywhenthesamplewassubmerged.

  • 标签: 钴基合金 ASTM 热处理 硅灰石 评价 F75
  • 简介:AbstractBipolar clavicular dislocation is rare, and therefore its management is contentious. With an increase of patient’s physical demand and a near-normal shoulder function, there has been a shift in the paradigm of its management from a conservative one to a stabilized one of anatomical open reduction. Proposed methods of fixation have also evolved with the advent of more biological fixation devices, which elude implant or fixation related complications. This case report highlights the salient features of this rare case and details the management options along with the benefits of biological anatomical repair and reconstruction.

  • 标签: Bipolar clavicular dislocation Traumatic floating clavicle Pan-clavicular dislocation Biological repair Surgical management
  • 简介:目的:探讨针灸治疗中风后偏瘫肩痛的临床疗效。方法:将90例中风后偏瘫肩痛患者按1:1:1随机分为3组。分别采用针灸、针灸加中药、中药进行治疗。结果:3组间疗效、全血黏度经统计学处理,针灸组、针灸加中药组与中药组相比具有显著性差异(P〈0.01);而针灸组与针灸加中药组之间无显著性差异(P〉0.05)。结论:针灸治疗对中风后偏瘫肩痛具有良好疗效,对异常全血黏度有近期调节降低作用。

  • 标签: 中风 并发症 肩痛 针灸疗法 血黏度
  • 简介:Objective:Toobservethetherapeuticeffectofcombinedcervicaltractionandelectroacupuncture(EA)onCervicalSpondylopathyofNerveRootType(CSNRT).Methods:145patientsdiagnosedasCSNRTwererandomizedinto3groups:combinedtreatmentgroup,EAgroup,andcervicaltraction(CT)group.Thecombinedgroupwastreatedwithtractionfollowed2),etc..PatientsoftwocontrolgroupswereonlytreatedbyeitherCTorEA.Results:Themarkedly-effectiverateandtotaleffectiveratewere76.0%and94.0%respectivelyinthecombinedtreatmentgroup,62.5%and81.25%respectivelyinCTgroup,and63.82%and82.97%respectivelyinEAgroup.Thetherapeuticeffectofthecombinedtreatmentgroupwassignificantlysuperiortothatoftwocontrolgroups(P<0.05).At6-monthfollow-up,theabovetwomarkedly-effectiveandtotaleffectiveratesinthecombinedtreatmentgroupremained74.0%and92.0%,stillsignificantlyhigherthanthatintwocontrolgroups.Conclusion:CombiningcervicletractionwithEAtreatmentcaneffectivelyeliminateorrelievethesymptomsandsignsinpatientswithnerveroottypecervicalspondylopathy.

  • 标签: 临床资料 颈椎病 神经根 头颈牵引架 电针刺 EA
  • 简介:Objective:Tostudytheroleofconnexingene(Cx43)onthedevelopmentofgliomaandthefeasibilityofusingCx43cDNAasatargetofgenetherapyofgliomas.Methods:ParentalratC6cellsandC6cellstransfectedwithCx43cDNAwereimplantedintorightcaudatenucleusofSDratsascontrolandtransfectedgroup.RatsbearingcerebralC6gliomasweretreatedwithCx43cDNAandemptyvectorastreatedgroupandemptyvectorgroup.Thegeneralmanifestation,survivaltime,MRIdynamicscanningandhistopathologicalchangesofallratswereobserved.Insituhybridizationandimmunohisto-chemistrywereusedforexaminationofCx43mRNAanditsproteiningliomas.AveragenumberofAgNORstainingwasusedfordetectionofcellproliferationactivity,andTUNELmethodfordeterminationofcellapoptosis.Results:Allratsincontrolandemptyvectorgroupdiedofcerebralgliomaswithin3weeksafterimplantationofC6cells.Sixoutofnineratsinthetransfectedgroupandeightoutoftenratsintreatedgroupkeptalivebeyond120dayswithtotallydisappearingofthetumorfoci,exceptonetreatedrathavingalittleresidueoftumor.IngliomasoftransfectedandtreatedgroupsCx43geneexpressionwasupregulated,proliferationactivitywaslowered,However,theapoptoticcellsdidnotincrease.Conclusion:ThepresentstudyindicatesthatCx43geneisofcrucialimportanceinthedevelopmentofmalignantglioma.Itcanbeaneffectivetargetforgenetherapyofgliomas.

  • 标签: C6神经胶质瘤 基因治疗 CX43基因 动物实验
  • 简介:BACKGROUND:Duringthecellularagingprocess,thenumberofmitochondria,generationofadenosinetriphosphate(ATP),activityofrespiratorychainenzymecomplex1and4,andoxidationdecrease.OBJECTIVE:Toobservetheeffectsofaqueousandspirituousextract,aswellaspolysaccharidesfromFructusschizandrae(MagnoliaVine)onenergymetabolismandmitochondrialanti-oxidationincranialnervecellsofaD-gal-inducedagingmousemodel.DESIGN,TIMEANDSETTING:Arandomized,controlled,animalstudy.TheexperimentwasconductedattheDepartmentofBiochemistry,QiqiharMedicalCollegebetweenMarchandJuly2006.MATERIALS:Fiftyhealthy,Kunmingmiceofbothsexes,aged2-3monthsoldandweighing18-22g,wereusedforthepresentstudy.FructusschizandraewaspurchasedfromtheMedicalCollegeofJiamusiUniversity.Aqueousextracts,spirituousextracts,andpolysaccharidesfromFructusschizandraewereprepared.D-galactose(D-gal)isaproductoftheSecondReagentFactory,ShanghaiCity,China.Mn-superoxidedismutase(Mn-SOD)kit,malonaldehyde(MDA)kit,proteinquantificationkit,andinorganicphosphorustestingkitwerepurchasedfromJianChengBioeng.Co.,China.METHODS:Fiftymicewererandomlydividedintofivegroups,with10miceineachgroup:youngcontrol,agingmodel,aqueousFructusschizandraeextract,spirituousFructusschizandraeextract,andFructusschizandraepolysaccharides.Overacourseof30days,miceinagingmodel,aqueousFructusschizandraeextract,spirituousFructusschizandraeextract,andFructusschizandraepolysaccharidesgroupswereinjectedsubcutaneouslywithD-gal(100mg/kg)intothenapeoftheneckdaily,andadministeredintragastricallywithanequalvolumeofsterile,warmwater(agingmodel),aqueousFructusschizandraeextract(2g/kg),spirituousFructusschizandraeextract(2g/kg),orFructusschizandraepolysaccharides(0.2g/kg),respectively.Miceintheyoungcontrolgroupwereinjectedintothenapeoftheneckwithphysiologicalsaline

  • 标签: 成年人 线粒体 神经细胞 复合酶